SCHEMBL7044210

SCHEMBL7044210

Cc1ccsc1-c1sc(-c2cccs2)cc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.40
CYP2E1 P05181 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2B6 P20813 1/20 0.40
CYP2C19 P33261 1/20 0.40
KDM4E B2RXH2 3/20 0.37
NPC1 O15118 3/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 3/20 0.37
LMNA P02545 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
RAB9A P51151 2/20 0.36
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
LTA4H P09960 1/20 0.35
ESR1 P03372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22734817 0.91 KDM4E (0.42) CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6
SCHEMBL9487879 0.86 CYP2A6 (0.40) CYP2A6CYP2E1CYP3A4CYP2D6CYP2C9
SCHEMBL22734779 0.86 DPP4 (0.47) KDM4ENPC1MAPTALDH1A1LMNA
SCHEMBL3195128 0.85 KDM4E (0.41) KDM4ENPC1MAPTALDH1A1LMNA
SCHEMBL12892635 0.83 MEN1 (0.42) KDM4ENPC1MAPTALDH1A1LMNA
SCHEMBL16533021 0.83 CYP2A6 (0.46) CYP2A6CYP2E1CYP3A4CYP2D6CYP2C9
SCHEMBL13125591 0.81 DPP4 (0.46) KDM4ENPC1MAPTALDH1A1LMNA
SCHEMBL14833009 0.80 MEN1 (0.36) KDM4ENPC1MAPTALDH1A1LMNA
SCHEMBL723960 0.79 CYP2A6 (0.44) CYP2A6CYP2E1CYP3A4CYP2D6CYP2C9
SCHEMBL498678 0.79 DPP4 (0.51) CYP2A6CYP2E1CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5415893-A Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1995-05-16 US claimed
EP-1357945-A2 METHOD TO PREVENT VISION LOSS QLT Inc. (CA) 2003-11-05 EP disclosed
EP-1357946-A2 REDUCED FLUENCE RATE PDT QLT Inc. (CA) 2003-11-05 EP disclosed
WO-2003007944-A1 TREATMENT OF MACULAR EDEMA WITH PHOTODYNAMIC THERAPY QLT, INC. (CA) 2003-01-30 WO disclosed
WO-2002062384-A2 REDUCED FLUENCE RATE PDT QLT INC. (CA) 2002-08-15 WO disclosed
WO-2002062385-A2 METHOD TO PREVENT VISION LOSS QLT, INC. (CA) 2002-08-15 WO disclosed
WO-2001085213-A2 SUPPORTS FOR PHOTOSENSITIZER FORMULATIONS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2001-11-15 WO disclosed
US-6315926-B1 HAZE-FREE DSM N.V. (NL) 2001-11-13 US disclosed
EP-0261837-B1 Process for the preparation of electrically conductive material SANYO ELECTRIC CO (JP) 2001-07-11 EP disclosed
EP-0821041-B1 Aqueous coating dispersion, process for the preparation thereof and use thereof in an anticorrosive paint DSM NV (NL) 2001-04-11 EP disclosed
EP-0821041-A2 Aqueous coating dispersion, process for the preparation thereof and use thereof in anticorrosive paint DSM N.V. (NL) 1998-01-28 EP disclosed
EP-0821040-A1 Aqueous coating dispersion, process for the preparation thereof and use thereof in anticorrosive paint DSM N.V. (NL) 1998-01-28 EP disclosed
EP-0342998-B1 Process for manufacturing an electrode for a solid electrolytic capacitor SANYO ELECTRIC CO (JP) 1996-01-17 EP disclosed
US-5415893-A Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1995-05-16 US disclosed
EP-0589529-A1 Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1994-03-30 EP disclosed
US-5019949-A Solid electrolytic capacitor SANYO ELECTRIC CO., LTD. (JP) 1991-05-28 US disclosed
US-4795687-A POLYTHIENYLENE, POLYPRYRROLE OR POLYANILINE MATERIAL PREPARED BY OXIDATION POLYMERIZATION MITSUBISHI KASEI CORP. (JP) 1989-01-03 US disclosed
EP-0261837-A2 Electrically conductive material and a process for the preparation of same and secondary battery using the electrically conductive material Sanyo Electric Co., Ltd (JP) 1988-03-30 EP disclosed
US-4731311-A Electrically conductive material and secondary battery using the electrically conductive material SANYO ELECTRIC CO., LTD. (JP) 1988-03-15 US disclosed
EP-0219063-A2 Process of manufacturing an electrically conductive material and a secondary battery using the electrically conductive material Sanyo Electric Co., Ltd (JP) 1987-04-22 EP disclosed