Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22734817 | 0.88 | KDM4E (0.42) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL22734779 | 0.83 | DPP4 (0.47) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL3195128 | 0.83 | KDM4E (0.41) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL27917354 | 0.81 | MEN1 (0.42) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL12892635 | 0.81 | MEN1 (0.42) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL7044210 | 0.80 | CYP2A6 (0.40) | KDM4ENPC1MAPTALDH1A1LMNA | |
| SCHEMBL13125591 | 0.78 | DPP4 (0.46) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL23947762 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL22733814 | 0.73 | KDM4E (0.35) | KDM4ENPC1MAPTALDH1A1LMNA | |
| SCHEMBL14960839 | 0.73 | HSD17B1 (0.43) | MEN1KMT2AKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760969-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | Switch Materials, Inc. (CA) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |