SCHEMBL498678

SCHEMBL498678

Cc1ccsc1-c1ccc(-c2cccs2)s1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.51
LTA4H P09960 1/20 0.49
ALDH1A1 P00352 6/20 0.46
KDM4E B2RXH2 4/20 0.46
GAA P10253 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
LMNA P02545 2/20 0.46
GLA P06280 2/20 0.46
MAPT P10636 2/20 0.46
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
MEN1 O00255 2/20 0.41
POLB P06746 2/20 0.41
HPGD P15428 2/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698354 1.00 DPP4 (0.51) DPP4LTA4HALDH1A1KDM4EGAA
SCHEMBL12445155 0.88 CYP2A6 (0.45) DPP4ALDH1A1KDM4EL3MBTL1NPC1
SCHEMBL19165108 0.88 CYP2A6 (0.45) DPP4ALDH1A1KDM4EL3MBTL1NPC1
SCHEMBL723960 0.86 CYP2A6 (0.44) DPP4LTA4HALDH1A1KDM4EGAA
SCHEMBL498545 0.86 CYP2A6 (0.47) ALDH1A1KDM4EL3MBTL1LMNAMAPT
Benzene SCHEMBL28459864 0.84 CYP2A6 (0.43) DPP4LTA4HALDH1A1KDM4EGAA
SCHEMBL13156364 0.81 DPP4 (0.50) DPP4LTA4HALDH1A1KDM4EGAA
SCHEMBL13125591 0.80 DPP4 (0.46) DPP4LTA4HALDH1A1KDM4EGAA
SCHEMBL23611278 0.79 DPP4 (0.65) DPP4LTA4HALDH1A1KDM4EGAA
SCHEMBL2742433 0.79 DPP4 (0.65) DPP4LTA4HALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5415893-A Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1995-05-16 US claimed
US-8106038-B2 Method for reducing or preventing PDT related inflammation QLT INC. (CA) 2012-01-31 US disclosed
US-8034803-B2 Treating an occult choroidal neovascular lesion QLT INC. (CA) 2011-10-11 US disclosed
US-20030087889-A1 Photodynamic therapy of occult age-related macular degeneration BAUSCH HEALTH COMPANIES INC. (CA) 2003-05-08 US disclosed
US-20030083649-A1 Method for reducing or preventing PDT related inflammation VALEANT SP. Z.O.O. (PL) 2003-05-01 US disclosed
US-6315926-B1 HAZE-FREE DSM N.V. (NL) 2001-11-13 US disclosed
EP-0261837-B1 Process for the preparation of electrically conductive material SANYO ELECTRIC CO (JP) 2001-07-11 EP disclosed
EP-0821041-B1 Aqueous coating dispersion, process for the preparation thereof and use thereof in an anticorrosive paint DSM NV (NL) 2001-04-11 EP disclosed
US-5993695-A ELECTROCONDUCTIVE PARTICLES COMPRISE AT LEAST A FIRST BINDER, A CONDUCTIVE POLYMER AND A NON-IONIC STABILIZER, CHARACTERIZED IN THAT THE COATING DISPERSION CONTAINS A SECOND BINDER DOES NOT FORM PART OF THE ELECTRICALLY CONDUCTIVE PARTICLES. DSM N.V. (NL) 1999-11-30 US disclosed
EP-0821040-A1 Aqueous coating dispersion, process for the preparation thereof and use thereof in anticorrosive paint DSM N.V. (NL) 1998-01-28 EP disclosed
EP-0821041-A2 Aqueous coating dispersion, process for the preparation thereof and use thereof in anticorrosive paint DSM N.V. (NL) 1998-01-28 EP disclosed
EP-0342998-B1 Process for manufacturing an electrode for a solid electrolytic capacitor SANYO ELECTRIC CO (JP) 1996-01-17 EP disclosed
US-5415893-A Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1995-05-16 US disclosed
EP-0219063-B1 Process of manufacturing an electrically conductive material and a secondary battery using the electrically conductive material SANYO ELECTRIC CO (JP) 1994-04-06 EP disclosed
EP-0589529-A1 Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1994-03-30 EP disclosed
US-5019949-A Solid electrolytic capacitor SANYO ELECTRIC CO., LTD. (JP) 1991-05-28 US disclosed
US-4795687-A POLYTHIENYLENE, POLYPRYRROLE OR POLYANILINE MATERIAL PREPARED BY OXIDATION POLYMERIZATION MITSUBISHI KASEI CORP. (JP) 1989-01-03 US disclosed
EP-0261837-A2 Electrically conductive material and a process for the preparation of same and secondary battery using the electrically conductive material Sanyo Electric Co., Ltd (JP) 1988-03-30 EP disclosed
EP-0219063-A2 Process of manufacturing an electrically conductive material and a secondary battery using the electrically conductive material Sanyo Electric Co., Ltd (JP) 1987-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087889-A1 Photodynamic therapy of occult age-related macular degeneration ALDH1A2, AGER, CRY2 DPP4 158/4885LTA4H 1026/4885ALDH1A1 262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.