Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | GMNN | O75496 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877973 | 0.89 | AR (0.40) | PTPN1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3871190 | 0.87 | PTPN1 (0.56) | PTPN1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3881528 | 0.86 | PTPN1 (0.42) | PTPN1ALDH1A1MAPTMEN1KMT2A | |
| Bromide SCHEMBL4048814 | 0.86 | PTPN1 (0.54) | PTPN1ALDH1A1MAPTMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL29625806 | 0.85 | PTPN1 (0.43) | PTPN1ALDH1A1MAPTMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL3872598 | 0.85 | PTPN1 (0.43) | PTPN1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3870778 | 0.80 | SMN1; SMN2 (0.37) | PTPN1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3877031 | 0.80 | PTPN1 (0.39) | PTPN1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3879944 | 0.79 | PTPN1 (0.38) | PTPN1ALDH1A1MAPTMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL926342 | 0.74 | ALDH1A1 (0.43) | PTPN1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030219680-A1 | Photoresists useful for microfabrication utilizing deep ultraviolet rays such as an excimer laser, x-rays such as synchrotron radiation, and electron beams | JSR CORPORATION (JP) | 2003-11-27 | — | — | US | disclosed |