Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 4/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045279 | 1.00 | CD38 (0.54) | CD38ALOX5ESR2ESR1APP | |
| SCHEMBL8424402 | 0.91 | ESR2 (0.46) | CD38ESR2ESR1APPCYP1A2 | |
| SCHEMBL30891532 | 0.90 | CD38 (0.55) | CD38ALOX5APPF2NR1H2 | |
| SCHEMBL6131749 | 0.90 | CD38 (0.55) | CD38ALOX5APPF2NR1H2 | |
| SCHEMBL6131735 | 0.90 | CD38 (0.64) | CD38ALOX5ESR2ESR1APP | |
| Hydrochloric Acid SCHEMBL6131737 | 0.88 | CD38 (0.62) | CD38ALOX5ESR2ESR1APP | |
| Hydrochloric Acid SCHEMBL6131736 | 0.88 | CD38 (0.54) | CD38ALOX5APPF2NR1H2 | |
| SCHEMBL6131734 | 0.85 | ESR1 (0.47) | CD38ESR2ESR1APPCYP1A2 | |
| SCHEMBL7045086 | 0.84 | CD38 (0.79) | CD38ALOX5ESR2ESR1APP | |
| Hydrochloric Acid SCHEMBL6131741 | 0.83 | ESR1 (0.46) | CD38ESR2ESR1APPGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007910-A1 | COMPOSITIONS COMPRISING COMPOUNDS OF FLAVYLIUM SALT TYPE UNSUBSTITUTED IN POSITION 3 FOR SKIN COLOURING AND USES | L'OREAL (FR) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007910-A1 | COMPOSITIONS COMPRISING COMPOUNDS OF FLAVYLIUM SALT TYPE UNSUBSTITUTED IN POSITION 3 FOR SKIN COLOURING AND USES | L'OREAL (FR) | 2003-01-30 | — | — | WO | disclosed |