Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6131741 | 0.98 | ESR1 (0.46) | ESR1ESR2ARMMP3BCL2L1 | |
| SCHEMBL8424402 | 0.93 | ESR2 (0.46) | ESR1ESR2ARMMP3BCL2L1 | |
| SCHEMBL7044449 | 0.85 | CD38 (0.54) | ESR1ESR2CYP1A2HSD17B1HSD17B2 | |
| SCHEMBL7045279 | 0.85 | CD38 (0.54) | ESR1ESR2CYP1A2HSD17B1HSD17B2 | |
| SCHEMBL29377385 | 0.84 | ALDH1A1 (0.35) | CYP1A2ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6131748 | 0.82 | CD38 (0.49) | ESR1ESR2CYP1A2HSD17B1HSD17B2 | |
| Hydrochloric Acid SCHEMBL6131744 | 0.81 | CD38 (0.47) | ESR1ESR2CYP1A2HSD17B1HSD17B2 | |
| SCHEMBL30891532 | 0.80 | CD38 (0.55) | APPCD38NPC1 | |
| SCHEMBL6131749 | 0.80 | CD38 (0.55) | APPCD38NPC1 | |
| Hydrochloric Acid SCHEMBL6131736 | 0.79 | CD38 (0.54) | APPCD38NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1172090-B1 | Skin dyeing compositions comprising dihydroxyacetone and a flavylium salt non substituted in position 3 | OREAL (FR) | 2005-03-09 | — | — | EP | claimed |
| EP-1172093-B1 | Compositions for coloring the skin containing flavylium salt compounds unsubstituted in position 3 and an organomodified silicone | OREAL (FR) | 2004-12-01 | — | — | EP | claimed |
| EP-1172092-B1 | Compositions for coloring the skin containing at least one UV filter and flavylium salt compounds unsubstituted in position 3 | OREAL (FR) | 2004-09-15 | — | — | EP | claimed |
| US-6558655-B2 | Substituted with at least one hydroxyl group or alkoxy radical. | Société l'Oréal S.A. (FR) | 2003-05-06 | — | — | US | claimed |
| US-6537528-B2 | Coloration close to that of a natural tan and which may be stable over time | L'OREAL S.A. (FR) | 2003-03-25 | — | — | US | claimed |
| US-6511656-B2 | Compositions for coloring the skin comprising at least one flavylium salt which is unsubstituted in position 3 and at least one organomodified silicone | L'OREAL S.A. (FR) | 2003-01-28 | — | — | US | claimed |
| US-6471949-B2 | COSMETICS; FOR ARTIFICIALLY COLORING THE SKIN | L'OREAL S.A. (FR) | 2002-10-29 | — | — | US | claimed |
| US-20020064507-A1 | Compositions comprising at least one UV screening agent and at least one flavylium salt which is unsubstituted in position 3, for coloring the skin, and uses thereof | L'OREAL S.A. (FR) | 2002-05-30 | — | — | US | claimed |
| US-20020051755-A1 | Composition comprising at least one self-tanning agent chosen from monocarbonyl and polycarbonyl compounds and a flavylium salt compound which is unsubstituted in position 3, for coloring the skin, and uses thereof | L'OREAL S.A. (FR) | 2002-05-02 | — | — | US | claimed |
| US-20020048555-A1 | Artificial tanning compositions comprising flavylium salts | SOCIETE L'OREAL S.A. (FR) | 2002-04-25 | — | — | US | claimed |
| US-20020048556-A1 | Compositions for coloring the skin comprising at least one flavylium salt which is unsubstituted in position 3 and at least one organomodified silicone | L'OREAL S.A (FR) | 2002-04-25 | — | — | US | claimed |
| EP-1172090-A1 | Skin dyeing compositions containing at least a mono or polycarbonyl self-tanning compound and a flavylium salt non substituted in position 3 | L'OREAL (FR) | 2002-01-16 | — | — | EP | claimed |
| EP-1172091-A1 | Skin dyeing compositions containing flavylium salt compounds non substituted in position 3 | L'OREAL (FR) | 2002-01-16 | — | — | EP | claimed |
| EP-1172093-A1 | Skin dyeing compositions containing flavylium salt compounds non substituted in position 3 and an organomodified silicone | L'OREAL (FR) | 2002-01-16 | — | — | EP | claimed |
| US-6241785-B1 | HOIR DYES | L'OREAL (FR) | 2001-06-05 | — | — | US | claimed |
| EP-0949897-B1 | USE OF FLAVYLIUM TYPE COMPOUNDS NON-SUBSTITUTED IN POSITION 3 FOR DYEING KERATINOUS FIBRES AND COMPOSITIONS CONTAINING THEM | OREAL (FR) | 2001-05-23 | — | — | EP | claimed |
| US-4376781-A | FLAVYLIUM SALTS HAVING HYPOLIPEMIC ANTIINFLAMMATORY, VASO-PROTECTIVE, HYPOCHOLESTEROLEMIC AND HYPOGLYCEMIC ACTIVITY | INVERNI DELLA BEFFA S.P.A. (IT) | 1983-03-15 | — | — | US | claimed |
| US-20050169856-A1 | Coloring composition, process of making, uses thereof | L'OREAL (FR) | 2005-08-04 | — | — | US | disclosed |
| US-6241785-B1 | HOIR DYES | L'OREAL (FR) | 2001-06-05 | — | — | US | disclosed |
| EP-0949897-B1 | USE OF FLAVYLIUM TYPE COMPOUNDS NON-SUBSTITUTED IN POSITION 3 FOR DYEING KERATINOUS FIBRES AND COMPOSITIONS CONTAINING THEM | OREAL (FR) | 2001-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020064507-A1 | Compositions comprising at least one UV screening agent and at least one flavylium salt which is unsubstituted in position 3, for coloring the skin, and uses thereof | TYR, CUTA, POLR1C | ESR1 2981/4885ESR2 2837/4885AR 1883/4885 |
| US-20020048556-A1 | Compositions for coloring the skin comprising at least one flavylium salt which is unsubstituted in position 3 and at least one organomodified silicone | CUTA, LPO, TYR | ESR1 929/4885ESR2 639/4885AR 354/4885 |
| US-20020048555-A1 | Artificial tanning compositions comprising flavylium salts | ADH7, TYR, HADHB | ESR1 2223/4885ESR2 2363/4885AR 825/4885 |
| US-20050169856-A1 | Coloring composition, process of making, uses thereof | CUTA, TYR, POLR1C | ESR1 4282/4885ESR2 4705/4885AR 3869/4885 |
| US-20020051755-A1 | Composition comprising at least one self-tanning agent chosen from monocarbonyl and polycarbonyl compounds and a flavylium salt compound which is unsubstituted in position 3, for coloring the skin, and uses thereof | TYR, CUTA, MITF | ESR1 3016/4885ESR2 3189/4885AR 1578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.