Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SMO | Q99835 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565638 | 0.87 | CA2 (0.47) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL6040509 | 0.81 | KDM4E (0.48) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL5559825 | 0.81 | ALDH1A1 (0.42) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL5564774 | 0.80 | ALDH1A1 (0.41) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL5560582 | 0.80 | ALDH1A1 (0.42) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL5560109 | 0.77 | KDM4E (0.40) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL5560099 | 0.77 | ALDH1A1 (0.40) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL5566299 | 0.76 | KAT6A (0.39) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL5565348 | 0.76 | ALDH1A1 (0.39) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL5566222 | 0.76 | KDM4E (0.39) | KDM4EMAPTMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108094-A2 | SULFONAMIDE-SUBSTITUTED CHALCONE DERIVATIVES AND THEIR USE TO TREAT DISEASES | ATHEROGENICS, INC. (US) | 2004-12-16 | — | — | WO | disclosed |