Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044710 | 0.81 | KDM4E (0.43) | CNR1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL7042639 | 0.81 | HPGD (0.52) | CNR1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL7044620 | 0.81 | KDM4E (0.49) | CNR1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL7048218 | 0.78 | — | — | |
| SCHEMBL7044998 | 0.76 | KDM4E (0.45) | CNR1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL7044567 | 0.74 | CSNK2A2 (0.47) | — | |
| SCHEMBL7047758 | 0.73 | KDM4E (0.51) | CNR1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL3455399 | 0.72 | LIMK2 (0.69) | ALDH1A1KMT2AMEN1HPGDGAA | |
| SCHEMBL7044199 | 0.71 | S1PR1 (0.52) | CNR1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL7232273 | 0.71 | ALOX5 (0.73) | ALDH1A1KMT2AMEN1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |