Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042639 | 0.92 | HPGD (0.52) | KDM4EHPGDSMN1; SMN2NOX1ALDH1A1 | |
| SCHEMBL6552039 | 0.79 | CNR1 (0.47) | HPGDSMN1; SMN2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL5274289 | 0.78 | KDM4E (0.58) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7046176 | 0.77 | NPC1 (0.51) | KDM4EHPGDSMN1; SMN2NOX1ALDH1A1 | |
| SCHEMBL7044567 | 0.76 | CSNK2A2 (0.47) | — | |
| SCHEMBL7046182 | 0.76 | PIN1 (0.42) | KDM4EHPGDSMN1; SMN2NOX1ALDH1A1 | |
| SCHEMBL11227523 | 0.75 | KDM4E (0.51) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6018249 | 0.75 | KDM4E (0.51) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4551697 | 0.75 | NOX1 (0.72) | KDM4EHPGDNOX1ALDH1A1KMT2A | |
| SCHEMBL7267270 | 0.75 | KDM4E (0.59) | KDM4EHPGDSMN1; SMN2NOX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |