SCHEMBL7044703

SCHEMBL7044703

CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Nc1cccc([N]C(N)=O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.39
MAPK1 P28482 5/20 0.39
NPSR1 Q6W5P4 5/20 0.39
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
ALDH1A1 P00352 2/20 0.39
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
MAPT P10636 5/20 0.35
HTT P42858 3/20 0.35
UBE2N P61088 2/20 0.35
MITF O75030 1/20 0.35
PARP1 P09874 1/20 0.34
PARP10 Q53GL7 1/20 0.34
SIRT2 Q8IXJ6 2/20 0.33
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10907411 0.88 SMN1; SMN2 (0.43) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL8616540 0.86 PARP1 (0.49) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL11514547 0.86 MAPK1 (0.43) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL14564633 0.84 KMT2A (0.46) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL14462088 0.84 SMN1; SMN2 (0.41) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL12548790 0.84 ALDH1A1 (0.43) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL11514545 0.84 SMN1; SMN2 (0.43) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL8616536 0.83 KMT2A (0.42) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL9814168 0.83 ALDH1A1 (0.47) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL10470820 0.82 SMN1; SMN2 (0.41) SMN1; SMN2MAPK1NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4310623-A THIO-PYRAZOLINE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US claimed
US-4264723-A CONTAINING PYRAZOLONE COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US claimed
EP-0763774-B1 Process for preparation of 2-equivalent 4-arylthio-5-pyrazolone magenta couplers TULALIP CONSULTORIA COM SOCIED (PT) 2003-04-02 EP disclosed
US-6156489-A Silver halide photosensitive material KONICA CORPORATION (JP) 2000-12-05 US disclosed
EP-0651289-B1 Photographic element containing an azopyrazolone masking coupler exhibiting reduced fogging EASTMAN KODAK CO (US) 1999-08-11 EP disclosed
US-5646297-A REACTING DIARYLSULFIDE AND 4-EQUIVALENT-5-PYRAZOLONE IN PRESENCE OF 1,8-DIAZABICYCLO-(5,4,0)-UNDECEN-7-ENE IN SOLVENT; SULFIDING IMATION CORP. (US) 1997-07-08 US disclosed
US-5641613-A SUPPORT BEARING LIGHT SENSITIVE SILVER HALIDE LAYER CONTAINING BICYCLIC AZOLE COUPLER, AZOPYRAZOLONE MASKING COUPLER, LOW IMPACT DEVELOPMENT INHIBITOR RELEASING COUPLER EASTMAN KODAK COMPANY (US) 1997-06-24 US disclosed
EP-0763774-A1 Process for preparation of 2-equivalent 4-arylthio-5-pyrazolone magenta couplers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-03-19 EP disclosed
EP-0646840-B1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK CO (US) 1997-01-29 EP disclosed
US-5591569-A Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1997-01-07 US disclosed
US-5482821-A Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1996-01-09 US disclosed
EP-0651289-A1 Photographic element containing an azopyrazolone masking coupler exhibiting reduced fogging EASTMAN KODAK COMPANY (US) 1995-05-03 EP disclosed
EP-0646841-A1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1995-04-05 EP disclosed
EP-0646840-A1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1995-04-05 EP disclosed
EP-0646842-A1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1995-04-05 EP disclosed
EP-0232101-B1 Light-sensitive silver halide color photographic material KONISHIROKU PHOTO IND (JP) 1994-03-23 EP disclosed
US-4587210-A COLORFASTNESS; DISCOLORATION INHIBITION; MAGENTA COUPLERS; WHITE BACKGROUND FUJI PHOTO FILM CO., LTD. (JP) 1986-05-06 US disclosed
US-4310623-A THIO-PYRAZOLINE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US disclosed
US-4293691-A Method for preparing magenta couplers having thioether groups FUJI PHOTO FILM CO., LTD. (JP) 1981-10-06 US disclosed
US-4264723-A CONTAINING PYRAZOLONE COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed