SCHEMBL8616540

SCHEMBL8616540

CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Nc1cccc(C(N)=O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 6/20 0.49
PARP10 Q53GL7 5/20 0.49
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
LMNA P02545 1/20 0.41
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
PARP14 Q460N5 2/20 0.38
PARP15 Q460N3 1/20 0.38
BRAF P15056 1/20 0.38
MITF O75030 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
UBE2N P61088 1/20 0.37
SIRT2 Q8IXJ6 2/20 0.36
MDH1 P40925 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12548790 0.92 ALDH1A1 (0.43) PARP1PARP10KMT2AMEN1ALDH1A1
SCHEMBL9814168 0.91 ALDH1A1 (0.47) PARP1PARP10KMT2AMEN1ALDH1A1
SCHEMBL8616536 0.91 KMT2A (0.42) PARP1PARP10KMT2AMEN1ALDH1A1
SCHEMBL10907411 0.90 SMN1; SMN2 (0.43) PARP1PARP10KMT2AMEN1ALDH1A1
SCHEMBL11514547 0.88 MAPK1 (0.43) PARP1PARP10KMT2AMEN1ALDH1A1
SCHEMBL14564633 0.87 KMT2A (0.46) KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2
SCHEMBL14462088 0.86 SMN1; SMN2 (0.41) KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2
SCHEMBL11716745 0.86 KMT2A (0.38) PARP1PARP10KMT2AMEN1ALDH1A1
SCHEMBL11514545 0.86 SMN1; SMN2 (0.43) KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2
SCHEMBL7044703 0.86 SMN1; SMN2 (0.39) PARP1PARP10KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4310619-A LIGHT SENSITIVE ELEMENT COMPRISING A 5-PYRAZOLONE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US claimed
US-4308343-A MAGENTA 2-EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US claimed
US-4301235-A A PYRAZOLONE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-11-17 US claimed
EP-0464612-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1998-05-13 EP disclosed
EP-0329088-B1 Processing method and bleaching solution for silver halide color photographic light-sensitive materials KONISHIROKU PHOTO IND (JP) 1997-04-23 EP disclosed
US-5529894-A PYRAZOLOAZOLE BASED MAGENTA COUPLER, TIMING COUPLER; SHARPNESS, DESILVERING PROPERTIES FUJI PHOTO FILM CO., LTD. (JP) 1996-06-25 US disclosed
EP-0438150-B1 Silver halide colour photographic material FUJI PHOTO FILM CO LTD (JP) 1995-04-26 EP disclosed
EP-0310125-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1995-04-19 EP disclosed
EP-0438129-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1995-04-12 EP disclosed
EP-0287073-B1 Method for processing a silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1995-03-08 EP disclosed
US-5360709-A Silver halide photographic material containing a DIR compound FUJI PHOTO FILM CO., LTD. (JP) 1994-11-01 US disclosed
EP-0127162-A2 Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-12-05 EP disclosed
US-4476219-A GALLIC AMIDE DERIVATIVE, HIGH SPEED REACTION COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1984-10-09 US disclosed
EP-0115305-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-08-08 EP disclosed
EP-0114675-A2 Color photographic silver halide light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-08-01 EP disclosed
US-4407936-A 5-PYRAZOLONE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1983-10-04 US disclosed
US-4310619-A LIGHT SENSITIVE ELEMENT COMPRISING A 5-PYRAZOLONE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US disclosed
US-4308343-A MAGENTA 2-EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US disclosed
US-4301235-A A PYRAZOLONE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-11-17 US disclosed
US-4171975-A MAGENTA COUPLER AND AN AMIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-10-23 US disclosed