Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.72 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.62 |
| ▸ | FABP1 | P07148 | 1/20 | 0.62 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355650 | 0.98 | HDAC1 (0.72) | FFAR4FFAR1HDAC1HDAC2HDAC3 | |
| SCHEMBL7365315 | 0.98 | HDAC1 (0.72) | FFAR4FFAR1HDAC1HDAC2HDAC3 | |
| SCHEMBL7046130 | 0.95 | FFAR4 (0.78) | FFAR4FFAR1HDAC1HDAC2HDAC3 | |
| SCHEMBL7049369 | 0.90 | FFAR4 (0.67) | FFAR4FFAR1HDAC1HDAC2HDAC3 | |
| SCHEMBL8987102 | 0.87 | LTB4R (0.64) | FFAR4FFAR1HDAC1HDAC2HDAC3 | |
| SCHEMBL30639265 | 0.86 | PPARA (0.58) | FFAR4FFAR1HDAC1HDAC2FABP1 | |
| SCHEMBL7367452 | 0.86 | HDAC1 (0.69) | FFAR4FFAR1HDAC1HDAC2HDAC3 | |
| SCHEMBL7044798 | 0.85 | HDAC1 (0.64) | FFAR4FFAR1HDAC1HDAC2HDAC3 | |
| SCHEMBL7044760 | 0.85 | HDAC1 (0.74) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL1162023 | 0.84 | PPARA (0.74) | FFAR4FFAR1HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874808-B1 | BIPHENYL HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LAB (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-0874808-A1 | BIPHENYL HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | Abbott Laboratories (US) | 1998-11-04 | — | — | EP | disclosed |
| US-5665777-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1997-09-09 | — | — | US | disclosed |
| WO-1997018188-A1 | BIPHENYL HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 1997-05-22 | — | — | WO | disclosed |