Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.72 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.64 |
| ▸ | FABP1 | P07148 | 1/20 | 0.64 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.59 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355650 | 1.00 | HDAC1 (0.72) | HDAC1HDAC2FFAR4FFAR1HDAC8 | |
| SCHEMBL7044733 | 0.98 | FFAR4 (0.72) | HDAC1HDAC2FFAR4FFAR1HDAC8 | |
| SCHEMBL7046130 | 0.94 | FFAR4 (0.78) | HDAC1HDAC2FFAR4FFAR1HDAC8 | |
| SCHEMBL8987102 | 0.89 | LTB4R (0.64) | HDAC1HDAC2FFAR4FFAR1HDAC8 | |
| SCHEMBL7049369 | 0.89 | FFAR4 (0.67) | HDAC1HDAC2FFAR4FFAR1HDAC8 | |
| SCHEMBL30639265 | 0.89 | PPARA (0.58) | HDAC1HDAC2FFAR4FFAR1FABP1 | |
| SCHEMBL7367452 | 0.88 | HDAC1 (0.69) | HDAC1HDAC2FFAR4FFAR1HDAC8 | |
| SCHEMBL7515225 | 0.85 | HDAC3 (0.77) | HDAC1HDAC2FFAR4FFAR1HDAC8 | |
| SCHEMBL1007408 | 0.85 | HDAC3 (0.77) | HDAC1HDAC2FFAR4FFAR1HDAC8 | |
| SCHEMBL3381443 | 0.85 | HDAC3 (0.77) | HDAC1HDAC2FFAR4FFAR1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020177594-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-11-28 | — | — | US | disclosed |
| US-20020103192-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-08-01 | — | — | US | disclosed |
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103192-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC5, HDAC4 | HDAC1 1/4885HDAC2 7/4885FFAR4 1771/4885 |
| US-20020177594-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC11, HDAC3 | HDAC1 1/4885HDAC2 4/4885FFAR4 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.