Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859579 | 1.00 | MCL1 (0.48) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL20049735 | 0.85 | MCL1 (0.57) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL181651 | 0.85 | MCL1 (0.52) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL11594648 | 0.85 | MCL1 (0.57) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL1081471 | 0.85 | AKR1C3 (0.56) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL792779 | 0.85 | AKR1C3 (0.56) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL17397066 | 0.85 | MCL1 (0.57) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL5982913 | 0.85 | AKR1C3 (0.56) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL10404442 | 0.83 | FBP1 (0.48) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL30733258 | 0.83 | AKR1C3 (0.59) | MCL1FBP1ALDH1A1TSHRAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916664-A1 | Enynes used in the synthesis of antifungal agents | Glaxo Wellcome, S.A. (ES) | 1999-05-19 | — | — | EP | claimed |
| EP-0957085-B1 | A process for the preparation of sulphonated distyryl-biphenyl compounds | CIBA SC HOLDING AG (CH) | 2003-03-26 | — | — | EP | disclosed |
| US-6096919-A | NEW SULPHONATED IMINE INTERMEDIATES | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0957085-A1 | A process for the preparation of sulphonated distyryl-biphenyl compounds | Ciba Spezialitätenchemie Holding AG (Ciba Spécialités Chimiques Holding SA) (Ciba Specialty Chemicals Holding Inc.) (CH) | 1999-11-17 | — | — | EP | disclosed |
| EP-0916664-A1 | Enynes used in the synthesis of antifungal agents | Glaxo Wellcome, S.A. (ES) | 1999-05-19 | — | — | EP | disclosed |
| US-4791174-A | VINYLAROMATIC/DIENE LIVING POLYMERS MODIFIED BY IMINE, HYDRAZONE OR AZINE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1988-12-13 | — | — | US | disclosed |
| US-3950279-A | DI- OR TRI-MALEIMIDE, AZOMETHINE, SOLID FOAMING AGENT | CIBA-GEIGY CORPORATION (US) | 1976-04-13 | — | — | US | disclosed |