SCHEMBL7045282

SCHEMBL7045282

CC1(C)Oc2ccc(C(=O)CO)cc2[C@H](NC(=O)c2ccc(F)cc2)[C@H]1O

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ABCC9 O60706 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7047495 0.93 ABCC9 (0.55) ABCC9
SCHEMBL7475675 0.91 ABCC9 (0.59) ABCC9
SCHEMBL7475685 0.91 ABCC9 (0.59) ABCC9
SCHEMBL7477937 0.91 ABCC9 (0.59) ABCC9
SCHEMBL7481173 0.89 ABCC9 (0.66) ABCC9
SCHEMBL7481178 0.89 ABCC9 (0.66) ABCC9
SCHEMBL7482702 0.89 ABCC9 (0.66) ABCC9
Carabersat SCHEMBL3301553 0.88 ABCC9 (0.62) ABCC9
Carabersat SCHEMBL3308650 0.88 ABCC9 (0.62) ABCC9
Carabersat SCHEMBL3300409 0.88 ABCC9 (0.62) ABCC9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1091950-B1 SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS SMITHKLINE BEECHAM PLC (GB) 2003-04-09 EP claimed
US-6395909-B1 DRUGS FOR ANTICONVULSANTS SMITHKLINE BEECHAM P.L.C. (GB) 2002-05-28 US claimed
EP-1091950-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP claimed
WO-2000000484-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS SMITHKLINE BEECHAM PLC (GB) 2000-01-06 WO claimed
US-20040024220-A1 Lipids CELLTECH R & D LIMITED 2004-02-05 US disclosed
EP-1091950-B1 SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS SMITHKLINE BEECHAM PLC (GB) 2003-04-09 EP disclosed
US-6395909-B1 DRUGS FOR ANTICONVULSANTS SMITHKLINE BEECHAM P.L.C. (GB) 2002-05-28 US disclosed
EP-1091950-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000000484-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS SMITHKLINE BEECHAM PLC (GB) 2000-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040024220-A1 Lipids PHOSPHO1, FABP7, MBOAT7 ABCC9 3265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.