⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18528138 | 0.91 | — | — | |
| SCHEMBL21295304 | 0.88 | ALDH1A1 (0.56) | — | |
| SCHEMBL8417525 | 0.88 | — | — | |
| SCHEMBL6924030 | 0.88 | ALDH1A1 (0.56) | — | |
| SCHEMBL3082520 | 0.80 | — | — | |
| SCHEMBL132364 | 0.79 | TSHR (0.67) | — | |
| SCHEMBL180666 | 0.79 | — | — | |
| SCHEMBL496221 | 0.76 | TSHR (0.72) | — | |
| SCHEMBL466419 | 0.76 | TSHR (0.72) | — | |
| SCHEMBL2154814 | 0.76 | TSHR (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041669-A | Epoxy resin monomer and preparation method and application thereof | 中国建筑材料科学研究总院有限公司 | 2023-05-02 | — | — | CN | disclosed |
| EP-3109230-B1 | CLASS OF CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN PREPARATION OF PRODRUGS | LI QINGENG (CN) | 2019-11-20 | — | — | EP | disclosed |
| EP-3109229-B1 | WATER-SOLUBLE PROPOFOL DERIVATIVES AND USES THEREOF | JIANGSU NHWALUOKANG PHARMACEUTICAL RES AND DEVELOPMENT CO LTD (CN) | 2019-06-05 | — | — | EP | disclosed |
| US-10239851-B2 | Carboxylic acid derivatives and use thereof in the preparation of prodrugs | Li, Qingeng (CN) | 2019-03-26 | — | — | US | disclosed |
| US-9643917-B2 | Water-soluble propofol derivatives and uses thereof | JIANGSU NHWALUOKANG PHARMCEUTICAL RESEARCH AND DEVELOPMENT CO., LTD (CN) | 2017-05-09 | — | — | US | disclosed |
| US-20170057939-A1 | CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN THE PREPARATION OF PRODRUGS | LI, Qingeng (CN) | 2017-03-02 | — | — | US | disclosed |
| US-9580444-B2 | Polycyclic pyrazolinone derivative and herbicide comprising same as effective component thereof | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2017-02-28 | — | — | US | disclosed |
| US-20170050920-A1 | WATER-SOLUBLE PROPOFOL DERIVATIVES AND USES THEREOF | JIANGSU NHWALUOKANG PHARMCEUTICAL RESEARCH AND DEVELOPMENT CO., LTD (CN) | 2017-02-23 | — | — | US | disclosed |
| EP-3109230-A1 | CLASS OF CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN PREPARATION OF PRODRUGS | Li, Qingeng (CN) | 2016-12-28 | — | — | EP | disclosed |
| EP-3109229-A1 | WATER-SOLUBLE PROPOFOL DERIVATIVES AND USES THEREOF | Jiangsu Nhwaluokang Pharmceutical Research and Development Co. Ltd. (CN) | 2016-12-28 | — | — | EP | disclosed |
| CN-103145715-A | Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of HCV replication | HOFFMANN LA ROCHE | 2013-06-12 | — | — | CN | disclosed |
| CN-102020697-A | Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication | INTERMUNE INC | 2011-04-20 | — | — | CN | disclosed |
| CN-1938311-A | Macrocyclic compounds as inhibitors of viral replication | INTERMUNE INC (US) | 2007-03-28 | — | — | CN | disclosed |
| CN-1229382-C | Semi-synthetic process and intermediates thereof | PHARMA MAR SA (ES) | 2005-11-30 | — | — | CN | disclosed |
| EP-1392779-A1 | FLUORINATED-PHOTOINITIATORS IN DUAL CURE RESINS | Ciba SC Holding AG (CH) | 2004-03-03 | — | — | EP | disclosed |
| CN-1360588-A | Hemisynthetic method and intermediate thereof | PHARMA MAR SA (ES) | 2002-07-24 | — | — | CN | disclosed |
| WO-2002040602-A1 | FLUORINATED-PHOTOINITIATORS IN DUAL CURE RESINS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-05-23 | — | — | WO | disclosed |
| US-5672701-A | 4-substituted alkyl carbapenem antibiotics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| CN-1030918-C | 4-substituted alkyl carbapenem antibiotics | BRISTOL MYERS SQUIBB CO (US) | 1996-02-07 | — | — | CN | disclosed |
| EP-0433759-A1 | 4-Substituted alkyl carbapenem antibiotics | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |