Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295304 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRTP53LMNANFKB1 | |
| SCHEMBL8417525 | 1.00 | — | — | |
| SCHEMBL18528138 | 0.97 | — | — | |
| SCHEMBL7045330 | 0.88 | — | — | |
| SCHEMBL2154814 | 0.85 | TSHR (0.72) | ALDH1A1TSHRTP53LMNANFKB1 | |
| SCHEMBL466419 | 0.85 | TSHR (0.72) | ALDH1A1TSHRTP53LMNANFKB1 | |
| SCHEMBL7329781 | 0.85 | TSHR (0.72) | ALDH1A1TSHRTP53LMNANFKB1 | |
| SCHEMBL495310 | 0.85 | TSHR (0.72) | ALDH1A1TSHRTP53LMNANFKB1 | |
| SCHEMBL6057206 | 0.85 | TSHR (0.72) | ALDH1A1TSHRTP53LMNANFKB1 | |
| SCHEMBL2154590 | 0.85 | TSHR (0.72) | ALDH1A1TSHRTP53LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082327-A4 | PERFLUORINATED ORGANO SUBSTITUTED CYCLOSILOXANES AND COPOLYMERS PREPARED FROM THESE CYCLOSILOXANES | CLARIANT LSM ITALIA SPA (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-1082327-A1 | PERFLUORINATED ORGANO SUBSTITUTED CYCLOSILOXANES AND COPOLYMERS PREPARED FROM THESE CYCLOSILOXANES | Archimica (Florida), Inc. (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999062916-A1 | PERFLUORINATED ORGANO SUBSTITUTED CYCLOSILOXANES AND COPOLYMERS PREPARED FROM THESE CYCLOSILOXANES | ARCHIMICA (FLORIDA) INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| US-4687602-A | Novel 2-substituted 3-sulfopropyl-ammonium betaines and processes for making same | AKADEMIE DER WISSENSCHAFTEN DER DDR (DD) | 1987-08-18 | — | — | US | disclosed |