Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038663 | 0.85 | HCRTR1 (0.47) | HCRTR1RXFP1KCNK3KCNK9GAA | |
| SCHEMBL7039865 | 0.84 | ABCB1 (0.52) | — | |
| SCHEMBL29778078 | 0.84 | ABCB1 (0.52) | — | |
| SCHEMBL30014073 | 0.81 | EZH2 (0.57) | EZH2HCRTR1KCNK3KCNK9GAA | |
| SCHEMBL28277840 | 0.80 | KAT6A (0.40) | GAAALDH1A1POLBKMT2A | |
| SCHEMBL8174016 | 0.77 | NPC1 (0.46) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL17624705 | 0.76 | CD38 (0.38) | HCRTR1ALDH1A1 | |
| SCHEMBL2345074 | 0.76 | PTGER1 (0.52) | EZH2HCRTR1MEN1KMT2A | |
| SCHEMBL28276332 | 0.75 | KCNK3 (0.40) | KCNK3KCNK9MAPTALDH1A1MEN1 | |
| SCHEMBL668914 | 0.75 | LMNA (0.46) | KCNK3KCNK9GAAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0982292-B1 | Process for the preparation of monoacylhydrazines using carboxylic acids | DOW AGROSCIENCES LLC (US) | 2003-03-26 | — | — | EP | disclosed |
| US-6096890-A | Process for substituted hydrazides using carboxylic acids | ROHM AND HAAS COMPANY (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0982292-A2 | Process for the preparation of monoacylhydrazines using carboxylic acids | ROHM AND HAAS COMPANY (US) | 2000-03-01 | — | — | EP | disclosed |