Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 18/20 | 0.56 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046434 | 0.90 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL7042512 | 0.83 | CNR1 (0.58) | CNR1CNR2PKM | |
| SCHEMBL7044680 | 0.82 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL7044571 | 0.81 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL6551978 | 0.77 | HTT (0.49) | CNR1CNR2 | |
| SCHEMBL7046420 | 0.77 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL7041816 | 0.73 | SMN1; SMN2 (0.53) | CNR1CNR2 | |
| SCHEMBL4084159 | 0.73 | CNR1 (0.78) | CNR1CNR2 | |
| SCHEMBL6552063 | 0.73 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL6552432 | 0.72 | CNR1 (0.57) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |