Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552432 | 0.90 | CNR1 (0.57) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL7045579 | 0.90 | CNR1 (0.57) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL7044217 | 0.89 | CNR1 (0.57) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL7043397 | 0.83 | CNR1 (0.58) | CNR1CNR2KMT2AALDH1A1HPGD | |
| SCHEMBL7045706 | 0.82 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL7043337 | 0.82 | CNR1 (0.56) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL7041065 | 0.81 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL7046441 | 0.81 | CNR1 (0.47) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL7043451 | 0.80 | CNR1 (0.55) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL7046412 | 0.79 | CNR1 (0.46) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |