Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.51 |
| ▸ | CA1 | P00915 | 10/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474468 | 0.98 | CA2 (0.50) | CA2CA1CA9PIK3CDPIK3CA | |
| SCHEMBL25453605 | 0.91 | CA2 (0.44) | CA2CA1CA9PIK3CDPIK3CA | |
| SCHEMBL6479936 | 0.90 | CA2 (0.45) | CA2CA1CA9PIK3CDPIK3CA | |
| Biphenyl SCHEMBL3395019 | 0.90 | PIK3CD (0.45) | CA2CA1CA9PIK3CDPIK3CA | |
| SCHEMBL15683037 | 0.88 | PIK3CD (0.44) | CA2CA1CA9PIK3CDPIK3CA | |
| SCHEMBL27366575 | 0.88 | PIK3CD (0.44) | CA2CA1CA9PIK3CDPIK3CA | |
| SCHEMBL6900759 | 0.88 | CA2 (0.46) | CA2CA1CA9PIK3CDPIK3CA | |
| Iodide SCHEMBL5315919 | 0.88 | PIK3CD (0.44) | CA2CA1CA9PIK3CDPIK3CA | |
| SCHEMBL575913 | 0.88 | CA2 (0.51) | CA2CA1CA9PIK3CDPIK3CA | |
| SCHEMBL20622597 | 0.86 | CA2 (0.45) | CA2CA1CA9PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| US-20030220386-A1 | Delta 1-pyrrolines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220386-A1 | Delta 1-pyrrolines for use as pesticides | DDT, OPRD1, PRMT1 | CA2 2815/4885CA1 2269/4885CA9 4337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.