SCHEMBL7046262

SCHEMBL7046262

Cc1ccc(S(=O)(=O)Oc2ccc3cccc4c3c2C(=O)NC4=O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
HPGD P15428 3/20 0.48
KDM4E B2RXH2 2/20 0.48
KMT2A Q03164 6/20 0.46
MEN1 O00255 5/20 0.46
PARP1 P09874 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
PKM P14618 2/20 0.43
ESR1 P03372 1/20 0.41
GAA P10253 1/20 0.41
ESR2 Q92731 1/20 0.41
LMNA P02545 3/20 0.40
MAPK1 P28482 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
VDR P11473 1/20 0.39
HTR6 P50406 1/20 0.39
MAPT P10636 2/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5668275 0.89 PARP1 (0.47) ALDH1A1HPGDKDM4EKMT2AMEN1
SCHEMBL3520419 0.85 KMT2A (0.50) ALDH1A1HPGDKDM4EKMT2AMEN1
SCHEMBL2041353 0.82 PARP1 (0.51) ALDH1A1HPGDKDM4EKMT2AMEN1
SCHEMBL84235 0.80 PARP1 (0.45) ALDH1A1HPGDKDM4EKMT2AMEN1
SCHEMBL1516405 0.77 PARP1 (0.47) ALDH1A1HPGDKDM4EKMT2AMEN1
SCHEMBL28678417 0.76 PARP1 (0.58) ALDH1A1KDM4EKMT2AMEN1PARP1
SCHEMBL594052 0.75 VDR (0.54) ALDH1A1HPGDKDM4EKMT2AMEN1
SCHEMBL3203317 0.75 PARP1 (0.56) ALDH1A1HPGDKDM4EKMT2AMEN1
SCHEMBL28228756 0.74 PARP1 (0.54) ALDH1A1HPGDKDM4EKMT2AMEN1
SCHEMBL7046260 0.73 KMT2A (0.46) ALDH1A1HPGDKMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102725339-B Use of protected n-hydroxyimide derivates and transition metal as oxygen scavenger system in transparent polyolefin films BASF SE 2014-08-13 CN disclosed
CN-102725339-A Use of protected n-hydroxyimide derivates and transition metal as oxygen scavenger system in transparent polyolefin films BASF SE 2012-10-10 CN disclosed
EP-1392675-A1 SUBSTITUTED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS Ciba SC Holding AG (CH) 2004-03-03 EP disclosed
WO-2002098870-A1 SUBSTITUTED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-12 WO disclosed