Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC37A4 | O43826 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694967 | 0.64 | PRSS1 (0.32) | SLC37A4 | |
| SCHEMBL7046306 | 0.64 | HPGD (0.33) | — | |
| SCHEMBL18272062 | 0.63 | CCNE2 (0.40) | ALDH1A1CYP3A4 | |
| SCHEMBL28171824 | 0.61 | AKR1C3 (0.34) | ALDH1A1 | |
| SCHEMBL530536 | 0.61 | SLC37A4 (0.56) | SLC37A4CA2ALDH1A1CYP3A4 | |
| SCHEMBL23544519 | 0.61 | KMT2A (0.49) | SLC37A4CA2ALDH1A1CYP3A4 | |
| SCHEMBL29361146 | 0.61 | KMT2A (0.49) | SLC37A4CA2ALDH1A1CYP3A4 | |
| SCHEMBL31454939 | 0.61 | KMT2A (0.49) | SLC37A4CA2ALDH1A1CYP3A4 | |
| SCHEMBL7044427 | 0.60 | APOBEC3G (0.38) | ALDH1A1CYP3A4KDM2B | |
| SCHEMBL1835324 | 0.60 | TSHR (0.38) | SLC37A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294697-A1 | 1,2,3,5-TETRAHYDROBENZO[C]AZEPIN-4-ONE DERIVATIVES HAVING MUSCARINIC ANTAGONIST ACTIVITY | Muscagen Limited (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002006241-A1 | 1, 2, 3, 5 -TETRAHYDROBENZO`C!AZEPIN-4-ONE DERIVATIVES HAVING MUSCARINIC ANTAGONIST ACTIVITY | MUSCAGEN LIMITED (GB) | 2002-01-24 | — | — | WO | disclosed |