Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044427 | 0.71 | APOBEC3G (0.38) | HPGD | |
| SCHEMBL6506891 | 0.69 | TSHR (0.38) | HPGD | |
| SCHEMBL8131345 | 0.68 | CYP1A2 (0.42) | — | |
| SCHEMBL18272062 | 0.65 | CCNE2 (0.40) | — | |
| SCHEMBL7046305 | 0.64 | SLC37A4 (0.33) | — | |
| SCHEMBL28171824 | 0.63 | AKR1C3 (0.34) | HPGD | |
| SCHEMBL7046538 | 0.62 | KMT2A (0.37) | HPGD | |
| SCHEMBL4609055 | 0.62 | BACE1 (0.45) | HPGDTRPM8 | |
| SCHEMBL28365429 | 0.61 | TSHR (0.54) | HPGDPRSS1PRSS2PRSS3 | |
| SCHEMBL28781318 | 0.61 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294697-A1 | 1,2,3,5-TETRAHYDROBENZO[C]AZEPIN-4-ONE DERIVATIVES HAVING MUSCARINIC ANTAGONIST ACTIVITY | Muscagen Limited (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002006241-A1 | 1, 2, 3, 5 -TETRAHYDROBENZO`C!AZEPIN-4-ONE DERIVATIVES HAVING MUSCARINIC ANTAGONIST ACTIVITY | MUSCAGEN LIMITED (GB) | 2002-01-24 | — | — | WO | disclosed |