Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7076221 | 0.98 | KDM4E (0.38) | KDM4EALDH1A1CYP2A6TSHRCYP1A2 | |
| SCHEMBL7046927 | 0.94 | KDM4E (0.37) | KDM4EALDH1A1CYP2A6TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL6063782 | 0.93 | KDM4E (0.36) | KDM4EALDH1A1CYP2A6TSHRCYP1A2 | |
| SCHEMBL6658743 | 0.85 | HTR7 (0.33) | KDM4EALDH1A1CYP2A6HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL7197428 | 0.82 | MAPT (0.35) | KDM4EALDH1A1CYP2A6MAPTALOX12 | |
| SCHEMBL5186539 | 0.81 | MEN1 (0.38) | KDM4EALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL9207240 | 0.77 | HTR2C (0.33) | ALDH1A1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL5185784 | 0.77 | CYP2D6 (0.38) | ALDH1A1CYP1A2HSD17B10POLBMEN1 | |
| SCHEMBL3123008 | 0.76 | ALDH1A1 (0.33) | ALDH1A1TSHRHSD17B10HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL2582956 | 0.76 | HTR2C (0.35) | ALDH1A1MEN1KMT2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058694-B1 | Catalyst system, method for its production and its use for the polymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2003-04-09 | — | — | EP | claimed |