⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777503 | 1.00 | — | — | |
| SCHEMBL6711919 | 0.96 | — | — | |
| SCHEMBL1071137 | 0.87 | ALDH1A1 (0.30) | — | |
| SCHEMBL7022582 | 0.86 | — | — | |
| SCHEMBL6950467 | 0.86 | — | — | |
| SCHEMBL909432 | 0.83 | — | — | |
| SCHEMBL4182682 | 0.83 | — | — | |
| SCHEMBL8217354 | 0.81 | SHBG (0.42) | — | |
| SCHEMBL9426205 | 0.79 | — | — | |
| Bromide SCHEMBL11400080 | 0.76 | SLC6A2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037365-A1 | DOUBLE-TARGET INHIBITOR TARGETING FGFR AND HDAC, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF, PHARMACEUTICAL COMPOSITION AND MEDICAMENT | 四川大学华西医院 | 2022-02-24 | — | — | WO | claimed |
| CN-112920167-A | Double-target inhibitor targeting FGFR and HDAC, preparation method and application thereof, pharmaceutical composition and medicament | 四川大学华西医院 | 2021-06-08 | — | — | CN | claimed |
| CN-108610246-A | A kind of Cyproconazole intermediate 1-（4- chlorphenyls）The preparation method of -2- cyclopropyl -1- acetone | 山东潍坊润丰化工股份有限公司 | 2018-10-02 | — | — | CN | claimed |
| CN-103201244-A | Processes for producing 1-bromo-2 (cyclopropyl methoxy)-5 fluoro-4- methoxybenzene | ALBEMARLE CORP | 2013-07-10 | — | — | CN | claimed |
| EP-0931055-A1 | SELECTIVE ALKYLATION OF AN ALCOHOL SUBSTITUTED PHENOL COMPOUND | Abbott Laboratories (US) | 1999-07-28 | — | — | EP | claimed |
| WO-1998012172-A1 | SELECTIVE ALKYLATION OF AN ALCOHOL SUBSTITUTED PHENOL COMPOUND | ABBOTT LABORATORIES (US) | 1998-03-26 | — | — | WO | claimed |
| US-12479794-B2 | Acetophenone oxime compound and application thereof | MEDSHINE DISCOVERY INC. (CN) | 2025-11-25 | — | — | US | disclosed |
| EP-3820860-B1 | PYRIDAZINE COMPOUNDS FOR INHIBITING NAV1.8 | LIEBER INST INC (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2025124459-A1 | TRICYCLIC FUSED HETEROCYCLIC PDE3/4 DUAL INHIBITOR, AND PREPARATION AND USE THEREFOR | 石家庄以岭药业股份有限公司 | 2025-06-19 | — | — | WO | disclosed |
| CN-120136868-A | Tricyclic fused heterocyclic PDE3/4 dual inhibitor and preparation method and application thereof | 石家庄以岭药业股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-119591621-A | Novel ecteinascidin derivatives, preparation method and application thereof, antibody drug conjugate and application thereof | 泰诚思(上海)生物医药有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-115697972-B | Receptor-interacting protein 1 inhibitors including piperazine heterocyclic amide urea | 维泰瑞隆有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-11993581-B2 | Pyridazine compounds for inhibiting Nav1.8 | LIEBER INSTITUE, INC (US) | 2024-05-28 | — | — | US | disclosed |
| EP-0208889-A1 | 2-Aza-substituted 1-carbadethiapen-2-EM-3-carboxylic acids | MERCK & CO. INC. (US) | 1987-01-21 | — | — | EP | disclosed |
| EP-0205272-A2 | Cinnoline derivatives | ICI AMERICAS INC. (US) | 1986-12-17 | — | — | EP | disclosed |
| EP-0173462-A2 | Ellipticine derivative and production process thereof | SUNTORY LIMITED (JP) | 1986-03-05 | — | — | EP | disclosed |
| US-4552883-A | CNS DEPRESSANTS, ANXIOLYTICS | ICI AMERICAS INC. (US) | 1985-11-12 | — | — | US | disclosed |
| EP-0096995-A2 | Pyrazolopyridine compounds | ICI AMERICAS INC. (US) | 1983-12-28 | — | — | EP | disclosed |
| US-4383946-A | Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals | MERCK & CO., INC. (US) | 1983-05-17 | — | — | US | disclosed |
| US-4235917-A | N-Alkyl-N-acyl derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-11-25 | — | — | US | disclosed |