Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | EBP | Q15125 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049028 | 0.82 | INPP5A (0.41) | SMPD1 | |
| SCHEMBL7047341 | 0.78 | INPP5A (0.43) | SMPD1 | |
| SCHEMBL7047326 | 0.74 | INPP5A (0.48) | SMPD1 | |
| SCHEMBL7047385 | 0.70 | INPP5A (0.42) | SMPD1 | |
| Phytic Acid SCHEMBL11523271 | 0.69 | LPAR3 (0.47) | SMPD1LPAR1LPAR3 | |
| Phytic Acid SCHEMBL11526614 | 0.69 | LPAR3 (0.47) | SMPD1LPAR1LPAR3 | |
| SCHEMBL3085645 | 0.69 | PDPK1 (0.50) | SIGMAR1GBA1 | |
| SCHEMBL3081758 | 0.68 | LPAR3 (0.55) | SMPD1GBA1LPAR1LPAR3 | |
| SCHEMBL3086058 | 0.68 | LPAR3 (0.55) | SMPD1GBA1LPAR1LPAR3 | |
| SCHEMBL17350929 | 0.68 | GUSB (0.70) | GUSBEBPSIGMAR1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023301-B1 | A HETEROCYCLIC CHEMICAL COMPOUND | BIONERIS AB (SE) | 2003-04-09 | — | — | EP | disclosed |
| US-6046334-A | Heterocyclic chemical compound | PERSTORP AB (SE) | 2000-04-04 | — | — | US | disclosed |