Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5A | Q14642 | 4/20 | 0.43 |
| ▸ | ITPR3 | Q14573 | 8/20 | 0.41 |
| ▸ | ITPR2 | Q14571 | 4/20 | 0.41 |
| ▸ | ITPR1 | Q14643 | 4/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049028 | 0.89 | INPP5A (0.41) | INPP5AITPR3ITPR2ITPR1SMPD1 | |
| SCHEMBL7046466 | 0.78 | GUSB (0.47) | SMPD1 | |
| SCHEMBL7047385 | 0.76 | INPP5A (0.42) | INPP5AITPR3ITPR2ITPR1SMPD1 | |
| SCHEMBL7047326 | 0.76 | INPP5A (0.48) | INPP5AITPR3ITPR2ITPR1SMPD1 | |
| SCHEMBL3085645 | 0.75 | PDPK1 (0.50) | — | |
| SCHEMBL7046732 | 0.70 | PDPK1 (0.53) | — | |
| SCHEMBL6295790 | 0.67 | INPP5A (0.63) | INPP5AITPR3ITPR2ITPR1SMPD1 | |
| SCHEMBL4269637 | 0.67 | INPP5A (0.63) | INPP5AITPR3ITPR2ITPR1SMPD1 | |
| SCHEMBL23356000 | 0.66 | INPP5A (0.62) | INPP5AITPR3ITPR2ITPR1SMPD1 | |
| SCHEMBL3083042 | 0.66 | INPP5A (0.50) | INPP5AITPR3ITPR2ITPR1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023301-B1 | A HETEROCYCLIC CHEMICAL COMPOUND | BIONERIS AB (SE) | 2003-04-09 | — | — | EP | disclosed |
| US-6046334-A | Heterocyclic chemical compound | PERSTORP AB (SE) | 2000-04-04 | — | — | US | disclosed |