Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085645 | 0.85 | PDPK1 (0.50) | PDPK1MTORGBA1SIGMAR1 | |
| SCHEMBL7050749 | 0.76 | PDPK1 (0.45) | PDPK1MTOR | |
| Phosphoric Acid SCHEMBL3115123 | 0.74 | CYP1A2 (0.57) | FUCA1S1PR5S1PR1GBA1SIGMAR1 | |
| SCHEMBL7114787 | 0.73 | PDPK1 (0.42) | PDPK1MTORALDH1A1 | |
| SCHEMBL7047385 | 0.72 | INPP5A (0.42) | — | |
| SCHEMBL18498897 | 0.72 | S1PR5 (0.53) | FUCA1S1PR5S1PR1 | |
| SCHEMBL8171730 | 0.70 | FUCA1 (0.53) | FUCA1S1PR5S1PR1SIGMAR1 | |
| SCHEMBL7047341 | 0.70 | INPP5A (0.43) | — | |
| SCHEMBL1978573 | 0.69 | PDPK1 (1.00) | PDPK1MTORALDH1A1 | |
| SCHEMBL8574542 | 0.69 | PDPK1 (1.00) | PDPK1MTORALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023301-B1 | A HETEROCYCLIC CHEMICAL COMPOUND | BIONERIS AB (SE) | 2003-04-09 | — | — | EP | disclosed |
| US-6046334-A | Heterocyclic chemical compound | PERSTORP AB (SE) | 2000-04-04 | — | — | US | disclosed |