SCHEMBL7046783

SCHEMBL7046783

Cc1nc(C)c(Cl)c(NCc2cc(OCC(F)(F)F)c(Oc3ccc4ncc([N+](=O)[O-])n4n3)c(Br)n2)n1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT2 Q96PD7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6741015 0.84 DGAT2 (0.33) DGAT2
SCHEMBL6884064 0.80 ALDH1A1 (0.31)
SCHEMBL6744173 0.79 GAA (0.39)
SCHEMBL6741165 0.79 GAA (0.37)
SCHEMBL6882952 0.78 ALDH1A1 (0.31)
Hydrochloric Acid SCHEMBL6882939 0.78 ALDH1A1 (0.31)
SCHEMBL6739835 0.78 STAT3 (0.39)
SCHEMBL6739562 0.77 CHRM4 (0.37)
SCHEMBL6742027 0.77 TSHR (0.35)
SCHEMBL6744446 0.77 SMN1; SMN2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1395592-A1 NOVEL PYRIDYLMETHYLAMINOPYRIMIDINES ALTANA Pharma AG (DE) 2004-03-10 EP disclosed
WO-2002094831-A1 NOVEL PYRIDYLMETHYLAMINOPYRIMIDINES ALTANA PHARMA AG (DE) 2002-11-28 WO disclosed