Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | F11 | P03951 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466411 | 0.89 | AR (0.78) | ARLMNATSHRSMN1; SMN2CCR2 | |
| SCHEMBL29071902 | 0.84 | AR (0.74) | ARLMNATSHRSMN1; SMN2NOTUM | |
| SCHEMBL6882430 | 0.82 | AR (0.75) | ARLMNATSHRSMN1; SMN2 | |
| SCHEMBL6466964 | 0.78 | AR (0.66) | ARLMNATSHRSMN1; SMN2FEN1 | |
| SCHEMBL6468911 | 0.76 | AR (1.00) | ARLMNATSHRSMN1; SMN2 | |
| SCHEMBL6889299 | 0.76 | AR (0.72) | ARLMNATSHRSMN1; SMN2FEN1 | |
| SCHEMBL29071900 | 0.75 | AR (0.70) | ARLMNATSHRSMN1; SMN2NOTUM | |
| SCHEMBL4484664 | 0.74 | CFTR (0.45) | ARLMNACCR2CFTRF11 | |
| SCHEMBL6469514 | 0.74 | AR (0.55) | ARLMNAMEN1KMT2A | |
| SCHEMBL6465994 | 0.73 | AR (0.79) | ARLMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | claimed |
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |