Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.39 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4492336 | 0.89 | AR (0.47) | FEN1GRIA2GRIA4ARALDH1A1 | |
| SCHEMBL4494579 | 0.86 | ALDH1A1 (0.43) | ARALDH1A1LMNA | |
| SCHEMBL4490747 | 0.85 | PGR (0.43) | CCR2SLC16A3MCTS1ALDH1A1LMNA | |
| SCHEMBL4559832 | 0.85 | TP53 (0.46) | FEN1ALDH1A1LMNA | |
| SCHEMBL4485732 | 0.82 | KMT2A (0.47) | CCR2FEN1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL4477472 | 0.81 | PGR (0.48) | CFTRCCR2FEN1ARALDH1A1 | |
| SCHEMBL4493743 | 0.80 | GRIA2 (0.39) | GRIA2GRIA4ALDH1A1LMNA | |
| SCHEMBL4485664 | 0.78 | KDM4E (0.40) | ALDH1A1LMNA | |
| SCHEMBL4490040 | 0.77 | GFER (0.47) | FEN1ALDH1A1 | |
| SCHEMBL4504902 | 0.75 | AR (0.57) | CFTRARALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |