Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 3/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584778 | 0.87 | KMT2A (0.53) | KMT2ACA1CA2TDP1MME | |
| SCHEMBL11305374 | 0.83 | KMT2A (0.47) | KMT2ACA1CA2POLBTDP1 | |
| SCHEMBL8192827 | 0.82 | KMT2A (0.43) | KMT2ACA1CA2MMEFOLH1 | |
| SCHEMBL8192831 | 0.82 | KMT2A (0.43) | KMT2ACA1CA2MMEFOLH1 | |
| SCHEMBL8669431 | 0.79 | KMT2A (0.47) | KMT2ACA1CA2MMEFOLH1 | |
| SCHEMBL9514344 | 0.79 | FOLH1 (0.48) | TDP1MMEFOLH1SMN1; SMN2TSHR | |
| SCHEMBL9725558 | 0.79 | FOLH1 (0.48) | TDP1MMEFOLH1SMN1; SMN2TSHR | |
| SCHEMBL14826510 | 0.77 | MME (0.45) | KMT2ACA1CA2TDP1MME | |
| SCHEMBL6053670 | 0.77 | CA2 (0.55) | KMT2ACA1CA2MMEFOLH1 | |
| SCHEMBL17092535 | 0.76 | HPGD (0.42) | KMT2ACA1CA2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042270-B1 | ASYMMETRIC HYDROGENATION | CHIROTECH TECHNOLOGY LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| US-6207853-B1 | SUCCINIC ACID DERIVATIVE | CHIROTECH TECHNOLOGY, INC. (GB) | 2001-03-27 | — | — | US | disclosed |
| EP-1042270-A1 | ASYMMETRIC HYDROGENATION | Chirotech Technology Limited (GB) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031041-A1 | ASYMMETRIC HYDROGENATION | CHIROTECH TECHNOLOGY LIMITED (GB) | 1999-06-24 | — | — | WO | disclosed |