SCHEMBL584778

SCHEMBL584778

COC(=O)C(CC(=O)O)CC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
FOLH1 Q04609 2/20 0.41
MME P08473 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
SLC22A6 Q4U2R8 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8669431 0.91 KMT2A (0.47) KMT2ACA1CA2FOLH1MME
SCHEMBL11305374 0.91 KMT2A (0.47) KMT2ACA1CA2FOLH1MME
SCHEMBL14826510 0.88 MME (0.45) KMT2ACA1CA2FOLH1MME
SCHEMBL6053670 0.88 CA2 (0.55) KMT2ACA1CA2FOLH1MME
SCHEMBL7046871 0.87 KMT2A (0.44) KMT2ACA1CA2FOLH1MME
SCHEMBL14193621 0.86 BMP1 (0.44) KMT2ACA1CA2FOLH1MME
SCHEMBL8192831 0.85 KMT2A (0.43) KMT2ACA1CA2FOLH1MME
SCHEMBL8192827 0.85 KMT2A (0.43) KMT2ACA1CA2FOLH1MME
SCHEMBL1177032 0.84 MME (0.58) KMT2ACA1CA2MME
SCHEMBL1177029 0.84 MME (0.58) KMT2ACA1CA2MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040086949-A1 Method for preparing a ligand presenting assembly (LPA), an LPA and uses thereof STATENS SERUM INSTITUT 2004-05-06 US claimed
EP-1117677-B1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF STATENS SERUMINSTITUT (DK) 2003-11-12 EP claimed
EP-1117677-A1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF Statens Serum Institut (DK) 2001-07-25 EP claimed
WO-2000018791-A1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF STATENS SERUM INSTITUT (DK) 2000-04-06 WO claimed
EP-2225272-B1 PEPTIDES DERIVED FROM NCAM (FGLS) ENKAM PHARMACEUTICALS AS (DK) 2015-10-21 EP disclosed
US-8470964-B2 Peptides derived from NCAM (FGLs) ENKAM PHARMACEUTICALS A/S (DK) 2013-06-25 US disclosed
EP-1765861-B1 FGFR BINDING PEPTIDES ENKAM PHARMACEUTICALS AS (DK) 2012-02-15 EP disclosed
US-20110098225-A1 NOVEL PEPTIDES DERIVED FROM NCAM (FGLs) COPENHAGEN UNIVERSITY 2011-04-28 US disclosed
EP-2225272-A2 NOVEL PEPTIDES DERIVED FROM NCAM (FGLS) Enkam Pharmaceuticals A/S (DK) 2010-09-08 EP disclosed
EP-1660539-B1 COMPOUNDS COMPRISING LPA ENKAM PHARMACEUTICALS AS (DK) 2010-06-02 EP disclosed
WO-2009068042-A2 NOVEL PEPTIDES DERIVED FROM NCAM (FGLS) ENKAM PHARMACEUTICALS A/S (DK) 2009-06-04 WO disclosed
US-20090105149-A1 Compounds comprising lpa ENKAM PHARMACEUTICALS A/S (DK) 2009-04-23 US disclosed
WO-2005014623-A9 COMPOUNDS COMPRISING LPA 2006-03-23 WO disclosed
WO-2005123759-A2 FGFR BINDING PEPTIDES ENKAM PHARMACEUTICALS A/S (DK) 2005-12-29 WO disclosed
WO-2005121168-A2 HEPARIN BINDING PEPTIDE ENKAM PHARMACEUTICALS A/S (DK) 2005-12-22 WO disclosed
WO-2005014623-A2 COMPOUNDS COMPRISING LPA ENKAM PHARMACEUTICALS A/S (DK) 2005-02-17 WO disclosed
US-20040086949-A1 Method for preparing a ligand presenting assembly (LPA), an LPA and uses thereof STATENS SERUM INSTITUT 2004-05-06 US disclosed
EP-1117677-B1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF STATENS SERUMINSTITUT (DK) 2003-11-12 EP disclosed
EP-1117677-A1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF Statens Serum Institut (DK) 2001-07-25 EP disclosed
WO-2000018791-A1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF STATENS SERUM INSTITUT (DK) 2000-04-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105149-A1 Compounds comprising lpa FGFR1, FGFR3, FGFR2 KMT2A 2819/4885CA1 3676/4885CA2 2421/4885
US-20110098225-A1 NOVEL PEPTIDES DERIVED FROM NCAM (FGLs) L1CAM, FGFR1, FGFR3 KMT2A 3741/4885CA1 2550/4885CA2 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.