SCHEMBL7046975

SCHEMBL7046975

CC(=O)NC12CCCCC1CCCC2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.56
MAPT P10636 1/20 0.34
KIF11 P52732 1/20 0.33
LIPA P38571 1/20 0.33
CTSD P07339 1/20 0.32
BACE1 P56817 1/20 0.32
BACE2 Q9Y5Z0 1/20 0.32
LMNA P02545 3/20 0.32
TSHR P16473 2/20 0.32
CYP3A4 P08684 2/20 0.31
ABCB11 O95342 1/20 0.31
CYP1A2 P05177 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
CYP2C9 P11712 1/20 0.31
CHRM3 P20309 1/20 0.31
DRD1 P21728 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11801116 0.98 HTT (0.58) HTTMAPTKIF11LIPACTSD
SCHEMBL23051874 0.85 HTT (0.43) HTTALDH1A1
SCHEMBL19069845 0.85 HTT (0.43) HTTALDH1A1
SCHEMBL6509736 0.83 HTT (0.45) HTTMAPTKIF11CYP1A2CHRM5
Hydrochloric Acid SCHEMBL7556945 0.82 HTT (0.44) HTTKIF11CYP1A2CHRM5CHRM3
SCHEMBL22479566 0.81 HTT (0.40) HTTMAPTLIPA
SCHEMBL3947129 0.77 HTT (0.40) HTTMAPTCTSDBACE1BACE2
SCHEMBL16790650 0.76 HTT (0.38) HTTKDM4EALDH1A1
Hydrochloric Acid SCHEMBL30853118 0.75 HTT (0.37) HTTTSHRCYP2D6KDM4EMEN1
SCHEMBL23573276 0.74 LMNA (0.33) HTTMAPTLMNATSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0990634-B1 ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES DAICEL CHEM (JP) 2013-04-10 EP disclosed
EP-1163194-B1 SELECTIVE NITROGEN FUNCTIONALISATION OF ORGANIC COMPOUNDS F2 CHEMICALS LTD (GB) 2003-04-09 EP disclosed
US-6441232-B1 PREFERENTIAL FLUORINATION F2 CHEMICALS LTD. (GB) 2002-08-27 US disclosed
US-6429314-B1 USING 1,2-DICARBONYL DERIVATIVE OR ITS HYDROXY REDUCTIVE, OXYGEN, COBALT ACETATE METAL COMPOUND, AND N-HYDROXYPHTHALIMIDE OR OTHER IMIDE DERIVATIVE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-08-06 US disclosed
EP-1163194-A1 SELECTIVE NITROGEN FUNCTIONALISATION OF ORGANIC COMPOUNDS F2 Chemicals Limited (GB) 2001-12-19 EP disclosed
WO-2001053234-A1 SELECTIVE NITROGEN FUNCTIONALISATION OF ORGANIC COMPOUNDS F2 CHEMICALS LIMITED (GB) 2001-07-26 WO disclosed
EP-0990634-A1 ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES Daicel Chemical Industries, Ltd. (JP) 2000-04-05 EP disclosed