SCHEMBL7047089

SCHEMBL7047089

Cc1c(Cl)cc(O)c(Cl)c1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 0.59
TSHR P16473 8/20 0.59
HPGD P15428 6/20 0.59
CYP3A4 P08684 5/20 0.59
HSP90AA1 P07900 1/20 0.59
ALDH1A1 P00352 3/20 0.44
ALOX15 P16050 2/20 0.40
MAPK1 P28482 2/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
CHRM1 P11229 1/20 0.40
MAOA P21397 1/20 0.40
TBXA2R P21731 1/20 0.40
ADRA1A P35348 1/20 0.40
HTR2B P41595 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
ACHE P22303 1/20 0.38
CASP1 P29466 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10935944 0.84 HSD17B10 (0.52) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL11055543 0.84 HSD17B10 (0.46) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL7023508 0.82 HSD17B10 (0.44) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL22138546 0.79 HSD17B10 (0.59) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL2468038 0.79 CYP3A4 (0.52) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL10592132 0.79 HSD17B10 (0.59) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL11060130 0.78 HSD17B10 (0.46) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL10820981 0.76 HSD17B10 (0.46) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL202648 0.75 HSD17B10 (1.00) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL1004018 0.75 CYP3A4 (0.59) HSD17B10TSHRHPGDCYP3A4HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785476-B1 Heat fixing method and use of a heat fixable toner CANON KK (JP) 2003-04-23 EP disclosed
US-5976753-A COPOLYMER EASTMAN KODAK COMPANY (US) 1999-11-02 US disclosed
US-5922499-A NEGATIVELY CHARGING TONERS WITH GOOD CHARGING CHARACTERISTICS AND POLYESTER BINDERS EASTMAN KODAK COMPANY (US) 1999-07-13 US disclosed
US-5922822-A AN ACRYLATE COPOLYMER CHARGE-CONTROL AGENTS IN ELECTROSTATOGRAPHIC TONERS AND DEVELOPERS EASTMAN KODAK COMPANY (US) 1999-07-13 US disclosed
US-5874194-A COPOLYMERIZED COMONOMER IS SELECTED FROM (METH)ACRYLIC ESTER, ACRYLIC ACID, ACRYLONITRILE, ALKYL ACRYLATE OR METHACRYLATE, ALKYL VINYL ETHER, VINYL ESTER, STYRENES, METHACRYLIC ACID, VINYL AMIDE, VINYL HALIDE, MALEIC ANHYDRIDE, METHACRYLAMIDE EASTMAN KODAK COMPANY (US) 1999-02-23 US disclosed
US-5849450-A (1,2-benzisothiazol-3-(2H)-ylidene 1,1-dioxide) acetate-terminated polymer charge-control agents for electrostatographic toners and developers EASTMAN KODAK COMPANY (US) 1998-12-15 US disclosed
US-5821025-A CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1998-10-13 US disclosed
US-5821024-A POLYESTER BINDER OF A DICARBOXYLIC ACID AND A POLYOL BLEND OF ETHERIFIED DIPHENOLS EASTMAN KODAK COMPANY (US) 1998-10-13 US disclosed
US-5814429-A Heat fixing method employing peelable film between heater and recording medium CANON KABUSHIKI KAISHA (JP) 1998-09-29 US disclosed
US-5804348-A COLORLESS, METAL-FREE, IMPROVE CHARGE UNIFORMITY EASTMAN KODAK COMPANY (US) 1998-09-08 US disclosed
US-5719000-A CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1998-02-17 US disclosed
US-5716749-A RAPIDLY CHARGING TONERS WHICH MAINTAIN CHARGES FOR EXTENDED TIMES EASTMAN KODAK COMPANY (US) 1998-02-10 US disclosed
US-5714295-A COLORLESS, METAL-FREE, RAPIDLY CHARGING TONERS WHICH MAINTAIN UNIFORM CHARGES FOR EXTENDED TIMES EASTMAN KODAK COMPANY (US) 1998-02-03 US disclosed
EP-0785476-A2 Heat fixing method and use of a heat fixable toner CANON KABUSHIKI KAISHA (JP) 1997-07-23 EP disclosed
US-5478686-A Fixable toner with a modified bisphenolic polyester resin CANON KABUSHIKI KAISHA (JP) 1995-12-26 US disclosed
EP-0373652-B1 Method of heat-fixing toner image CANON KK (JP) 1995-09-13 EP disclosed
EP-0421416-A2 Heat fixable toner and heat fixing method CANON KABUSHIKI KAISHA (JP) 1991-04-10 EP disclosed
US-4957774-A HEATING AND PRESSING THROUGH A FILM CONTACTING THE TONER IMAGE, CONTROLLING MELT VISCOSITY OF TONER CANON KABUSHIKI KAISHA (JP) 1990-09-18 US disclosed
EP-0373652-A2 Method of heat-fixing toner image CANON KABUSHIKI KAISHA (JP) 1990-06-20 EP disclosed
US-4533614-A BINDER IS LOW MELTING POLYESTER CANON KABUSHIKI KAISHA (JP) 1985-08-06 US disclosed