SCHEMBL202648

SCHEMBL202648

Oc1cc(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 11/20 1.00
TSHR P16473 11/20 1.00
HPGD P15428 8/20 1.00
CYP3A4 P08684 7/20 1.00
HSP90AA1 P07900 2/20 1.00
ALDH1A1 P00352 5/20 0.57
MAPK1 P28482 3/20 0.52
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
CASP1 P29466 1/20 0.50
AKR1B1 P15121 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 2/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
RECQL P46063 2/20 0.39
NPC1 O15118 1/20 0.39
USP2 O75604 1/20 0.39
EGFR P00533 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30375662 1.00 HSD17B10 (1.00) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL27616586 0.97 HSD17B10 (0.94) HSD17B10TSHRHPGDCYP3A4HSP90AA1
Lithium SCHEMBL30477954 0.97 HSD17B10 (0.94) HSD17B10TSHRHPGDCYP3A4HSP90AA1
Water SCHEMBL31080947 0.97 HSD17B10 (0.94) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL30477955 0.97 HSD17B10 (0.94) HSD17B10TSHRHPGDCYP3A4HSP90AA1
Pentachlorophenol SCHEMBL10591274 0.92 HSD17B10 (0.84) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL1259609 0.83 HSD17B10 (0.70) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL8644431 0.83 HSD17B10 (0.71) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL23879337 0.82 TSHR (0.71) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL6754079 0.81 HSD17B10 (0.68) HSD17B10TSHRHPGDCYP3A4HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1995 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678240-A2 BRIDGE LINKERS FOR CONJUGATION OF CELL-BINDING MOLECULES Hangzhou Dac Biotech Co., Ltd. (CN) 2026-01-14 EP claimed
EP-3319936-B1 BRIDGE LINKERS FOR CONJUGATION OF CELL-BINDING MOLECULES HANGZHOU DAC BIOTECH CO LTD (CN) 2025-12-17 EP claimed
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-16 US claimed
US-12472265-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-11-18 US claimed
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 US claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
US-12433950-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-10-07 US claimed
EP-4621008-A1 LIGHTWEIGHT MATERIAL, PREPARATION METHOD FOR AIR DEFLECTOR, AIR DEFLECTOR ASSEMBLY, AND AUTOMOBILE Zhejiang Geely Holding Group Co., Ltd. (CN) 2025-09-24 EP claimed
CN-120121751-A Method for detecting chlorophenols in waste gas and application thereof 华电莱州发电有限公司 2025-06-10 CN claimed
EP-0057153-A2 Biocidal substances containing emulsifiable concentrates, aqueous emulsions obtained therefrom and utilization thereof for treating wood XYLOCHIMIE (FR) 1982-08-04 EP claimed
US-4294996-A Method of reducing formation of chlorinated dioxins in manufacture of chlorinated phenols REICHHOLD CHEMICALS, INCORPORATED (US) 1981-10-13 US claimed
US-4288249-A Water soluble pentachlorophenol and tetrachlorophenol wood treating systems REICHHOLD CHEMICALS, INC. (US) 1981-09-08 US claimed
US-4280012-A DETOXIFICATION USING ACETYLENE OR HYDRAZINE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1981-07-21 US claimed
US-4236973-A BY PASSING A CURRENT OF VAPOR THROUGH A MOVING STREAM TO VAPORIZE ANY ORGANICS THE DOW CHEMICAL COMPANY (US) 1980-12-02 US claimed
US-4169049-A USING BACTERIA BIOFILTER CONTAINING CONIFEROUS BARK TO DECOMPOSE CHLORINATED PHENOL POLLUTANTS ENSO-GUTZEIT OSAKEYHTIO (FI) 1979-09-25 US claimed
US-4103450-A LOW DENSITY WEB IMPREGNATED WITH INSECTICIDE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-08-01 US claimed
US-3984417-A Method of producing active amino acid esters AJINOMOTO CO., INC. (JA) 1976-10-05 US claimed
US-3971717-A CHLOROPHENOL, DECOMPOSITION GESELLSCHAFT FUR KERNFORSCHUNG M.B.H. (DT) 1976-07-27 US claimed
US-3933783-A Formation of peptide bonds in the presence of isonitriles AJINOMOTO CO., INC. (JA) 1976-01-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES FCGR2A, FCGR3B, FCGR1A HSD17B10 2953/4885TSHR 1062/4885HPGD 3598/4885
US-12433950-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM HSD17B10 885/4885TSHR 3166/4885HPGD 2079/4885
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM HSD17B10 885/4885TSHR 3166/4885HPGD 2079/4885
US-12472265-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM HSD17B10 885/4885TSHR 3166/4885HPGD 2079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.