SCHEMBL7023508

SCHEMBL7023508

Cc1c(Cl)cc(O)c(O)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 9/20 0.44
TSHR P16473 8/20 0.44
HPGD P15428 6/20 0.44
CYP3A4 P08684 5/20 0.44
HSP90AA1 P07900 1/20 0.44
SELL P14151 1/20 0.42
SELP P16109 1/20 0.42
SELE P16581 1/20 0.42
CASP1 P29466 1/20 0.42
ALDH1A1 P00352 4/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 2/20 0.39
MAPK1 P28482 1/20 0.39
CHRM1 P11229 1/20 0.39
MAOA P21397 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
HTR2B P41595 1/20 0.39
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26018812 0.82 HSD17B10 (0.43) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL4450834 0.82 HSD17B10 (0.43) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL7047089 0.82 HSD17B10 (0.59) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL10771021 0.82 HSD17B10 (0.59) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL11055543 0.82 HSD17B10 (0.46) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL157575 0.80 CYP3A4 (0.44) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL5589371 0.80 ALOX15 (0.50) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL2659253 0.80 HSD17B10 (0.50) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL22454878 0.77 HSD17B10 (0.43) HSD17B10TSHRHPGDCYP3A4HSP90AA1
SCHEMBL10935944 0.77 HSD17B10 (0.52) HSD17B10TSHRHPGDCYP3A4HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1276780-A2 POLYMERIZABLE COMPOSITION OF ALLYL FUNCTIONAL MONOMERS PPG Industries Ohio, Inc. (US) 2003-01-22 EP disclosed
WO-2001077194-A2 POLYMERIZABLE COMPOSITION OF ALLYL FUNCTIONAL MONOMERS PPG INDUSTRIES OHIO, INC. (US) 2001-10-18 WO disclosed