Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 2/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | PROC | P04070 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049735 | 0.88 | F2 (0.40) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7991189 | 0.88 | F2 (0.44) | F2F10PLGPLATPRSS1 | |
| Hydrochloric Acid SCHEMBL6485317 | 0.83 | ITGB3 (0.38) | F2F10PLGPLATPRSS1 | |
| Hydrochloric Acid SCHEMBL8721658 | 0.83 | F2 (0.40) | F2F10PLGPLATPRSS1 | |
| SCHEMBL6487745 | 0.80 | ITGB3 (0.36) | F2F10PLGPLATPRSS1 | |
| SCHEMBL6475692 | 0.79 | ITGB3 (0.36) | F2F10PLGPLATPRSS1 | |
| SCHEMBL6477095 | 0.79 | F2 (0.38) | F2F10F7PROC | |
| SCHEMBL6475562 | 0.79 | F2 (0.38) | F2F10F7PROC | |
| SCHEMBL6484519 | 0.78 | ITGB3 (0.36) | F2F10PLGPLATPRSS1 | |
| SCHEMBL6485408 | 0.77 | ITGB3 (0.34) | F2F10PLGPLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773955-B1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | BASF AG (DE) | 2003-04-16 | — | — | EP | disclosed |