Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.34 |
| ▸ | PROC | P04070 | 2/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047178 | 0.88 | F2 (0.48) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7049735 | 0.83 | F2 (0.40) | F2F10PLGPLATPRSS1 | |
| Hydrochloric Acid SCHEMBL8721658 | 0.81 | F2 (0.40) | F2F10PLGPLATPRSS1 | |
| SCHEMBL6476613 | 0.76 | F2 (0.42) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7049734 | 0.76 | NAMPT (0.37) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7987916 | 0.75 | F2 (0.39) | F2F10PLGPLATPRSS1 | |
| Hydrochloric Acid SCHEMBL8933094 | 0.75 | F2 (0.38) | F2F10PLGPLATPRSS1 | |
| SCHEMBL6487745 | 0.72 | ITGB3 (0.36) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7987041 | 0.72 | NAMPT (0.37) | F2F10PLGPLATPRSS1 | |
| SCHEMBL6486760 | 0.71 | PRSS1 (0.38) | F2PRSS1PRSS2PRSS3F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204385-B1 | REACTING THE CORRESPONDING NITRILE WITH AMMONIA, AMINE OR HYDRAZINE IN THE PRESENCE OF A MERCAPTOCARBOXYLIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-20 | — | — | US | disclosed |
| EP-0931069-B1 | PROCESS FOR PREPARING AMIDINES | BASF AG (DE) | 2000-11-29 | — | — | EP | disclosed |