⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28700224 | 0.93 | — | — | |
| SCHEMBL6579636 | 0.80 | S1PR1 (0.35) | — | |
| SCHEMBL2167978 | 0.80 | HSD11B1 (0.35) | — | |
| SCHEMBL29431938 | 0.80 | — | — | |
| SCHEMBL19199020 | 0.77 | ROCK2 (0.34) | — | |
| SCHEMBL18602494 | 0.75 | ROCK2 (0.33) | — | |
| SCHEMBL18150680 | 0.73 | — | — | |
| SCHEMBL27615430 | 0.72 | TSHR (0.34) | — | |
| SCHEMBL19121494 | 0.72 | ROCK2 (0.34) | — | |
| Water SCHEMBL28579855 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004564-B1 | Process for the preparation of hydroxyethylcyclohexanes and hydroxyethylpiperidines | BAYER AG (DE) | 2003-04-16 | — | — | EP | disclosed |
| US-6268501-B1 | CATALYTIC HYDROGENATION OF HYDROXYETHYL PYRIDINE, WHEREIN RUTHENIUM WHICH HAS BEEN TREATED BEFORE USE WITH REDUCING AGENT IS USED AS CATALYST TO FORM HYDROXYETHYL CYCLONEXANE THAT CONTAINS NITROGEN ATOM IN CYCLOHEXANE RING | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-31 | — | — | US | disclosed |
| EP-1004564-A1 | Process for the preparation of hydroxyethylcyclohexanes and hydroxyethylpiperidines | Bayer Aktiengesellschaft (DE) | 2000-05-31 | — | — | EP | disclosed |