Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244841 | 0.91 | — | — | |
| SCHEMBL27865433 | 0.88 | SMN1; SMN2 (0.36) | LMNAHTTSMN1; SMN2CA1CA2 | |
| Hydrochloric Acid SCHEMBL9087948 | 0.88 | SMN1; SMN2 (0.36) | LMNAHTTSMN1; SMN2CA1CA2 | |
| Benzene SCHEMBL8096224 | 0.83 | LMNA (0.38) | LMNAHTTSMN1; SMN2SERPINE1NPC1 | |
| Propane SCHEMBL5572675 | 0.82 | CA1 (0.38) | CA1CA2 | |
| SCHEMBL242727 | 0.78 | — | — | |
| SCHEMBL27536481 | 0.78 | — | — | |
| Propionic Acid SCHEMBL9764191 | 0.77 | FFAR3 (0.48) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL5252426 | 0.76 | CA1 (0.55) | LMNAHTTSMN1; SMN2CA1CA2 | |
| SCHEMBL8429954 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299914-B2 | 9-Halogen (Z) prostaglandin derivatives, process for their production and their use as medicines | SCHERING AG (DE) | 2003-04-23 | — | — | EP | disclosed |