Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244841 | 0.84 | — | — | |
| Benzene SCHEMBL8096224 | 0.82 | LMNA (0.38) | SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL27865433 | 0.82 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2ALMNAHTTHPGD | |
| Hydrochloric Acid SCHEMBL9087948 | 0.82 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2ALMNAHTTHPGD | |
| SCHEMBL11403247 | 0.77 | ALDH1A1 (0.41) | FFAR3KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL7047499 | 0.77 | LMNA (0.33) | SMN1; SMN2LMNAHTT | |
| Propionic Acid SCHEMBL2777824 | 0.76 | FFAR3 (0.71) | FFAR3KMT2AHDAC3HDAC1HDAC2 | |
| Propionic Acid SCHEMBL28174768 | 0.76 | FFAR3 (0.71) | FFAR3KMT2AHDAC3HDAC1HDAC2 | |
| Propionic Acid SCHEMBL5073547 | 0.73 | FFAR3 (0.67) | FFAR3KMT2AHDAC3HDAC1HDAC2 | |
| Propionic Acid SCHEMBL28589623 | 0.73 | FFAR3 (0.67) | FFAR3KMT2AHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419653-A4 | DERIVATIVES OF TAXOL, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS FOR THE PREPARATION THEREOF | — | 1991-12-04 | — | — | EP | disclosed |
| EP-0419653-A1 | DERIVATIVES OF TAXOL, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS FOR THE PREPARATION THEREOF | THE UNIVERSITY OF KANSAS (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4960790-A | ANTITUMOR AGENTS, WATER SOLUBLE | UNIVERSITY OF KANSAS (US) | 1990-10-02 | — | — | US | disclosed |
| WO-1990010443-A1 | DERIVATIVES OF TAXOL, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS FOR THE PREPARATION THEREOF | UNIVERSITY OF KANSAS (US) | 1990-09-20 | — | — | WO | disclosed |