Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941725 | 1.00 | SORD (1.00) | SORD | |
| SCHEMBL9450503 | 0.85 | SORD (0.74) | SORD | |
| Hydrochloric Acid SCHEMBL9450505 | 0.84 | SORD (0.72) | SORD | |
| SCHEMBL6293147 | 0.82 | SORD (0.70) | SORD | |
| SCHEMBL7588700 | 0.81 | SORD (0.68) | SORD | |
| SCHEMBL6585366 | 0.79 | SORD (1.00) | SORD | |
| SCHEMBL6586568 | 0.79 | SORD (1.00) | SORD | |
| SCHEMBL6585364 | 0.79 | SORD (1.00) | SORD | |
| SCHEMBL6348271 | 0.78 | SORD (0.64) | SORD | |
| SCHEMBL6587390 | 0.78 | SORD (0.64) | SORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0864327-B1 | Use of pyrimidin derivatives for the manufacture of a medicament to prevent cancer | HOECHST AG (DE) | 2002-11-06 | — | — | EP | claimed |
| EP-0791355-B1 | Method of reducing tissue damage associated with ischemia | PFIZER (US) | 2002-04-17 | — | — | EP | claimed |
| US-6156755-A | Use of pyrimidine derivatives for the prevention of cancer, on their own or in combination with other therapeutic measures | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-12-05 | — | — | US | claimed |
| US-5932581-A | ADMINISTERING SORBITOL DEHYDROGENASE INHIBITOR | PFIZER INC. (US) | 1999-08-03 | — | — | US | claimed |
| EP-0864327-A1 | Use of pyrimidin derivatives to prevent cancer | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-16 | — | — | EP | claimed |
| EP-0791355-A1 | Method of reducing tissue damage associated with ischemia | PFIZER INC. (US) | 1997-08-27 | — | — | EP | claimed |
| JP-9316004-A | — | — | None | — | — | JP | disclosed |
| US-20030119160-A1 | Three dimensional crystal structure of human sorbitol dehydrogenase and uses thereof | MYLARI BANAVARA L (US) | 2003-06-26 | — | — | US | disclosed |
| WO-2003033643-A2 | THREE DIMENSIONAL CRYSTAL STRUCTURE OF HUMAN SORBITOL DEHYDROGENASE AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2003-04-24 | — | — | WO | disclosed |
| EP-1302538-A2 | Three dimensional crystal structure of human sorbitol dehydrogenase and uses thereof | Pfizer Products Inc. (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-0864327-B1 | Use of pyrimidin derivatives for the manufacture of a medicament to prevent cancer | HOECHST AG (DE) | 2002-11-06 | — | — | EP | disclosed |
| EP-0791355-B1 | Method of reducing tissue damage associated with ischemia | PFIZER (US) | 2002-04-17 | — | — | EP | disclosed |
| US-6156755-A | Use of pyrimidine derivatives for the prevention of cancer, on their own or in combination with other therapeutic measures | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-12-05 | — | — | US | disclosed |
| US-5932581-A | ADMINISTERING SORBITOL DEHYDROGENASE INHIBITOR | PFIZER INC. (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0864327-A1 | Use of pyrimidin derivatives to prevent cancer | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-16 | — | — | EP | disclosed |
| JP-H09316004-A | MEDICINE FOR REDUCING INJURY OF TISSUE ACCOMPANIED BY ISCHEMIA | PFIZER INC | 1997-12-09 | — | — | JP | disclosed |
| EP-0791355-A1 | Method of reducing tissue damage associated with ischemia | PFIZER INC. (US) | 1997-08-27 | — | — | EP | disclosed |
| EP-0470616-B1 | Substituted pyrimidin derivatives, process for their preparation and their use as reagent | HOECHST AG (DE) | 1997-02-19 | — | — | EP | disclosed |
| US-5215990-A | Screening for aldose reductase inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0470616-A2 | Substituted pyrimidin derivatives, process for their preparation and their use as reagent | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-12 | — | — | EP | disclosed |