SCHEMBL7047679

SCHEMBL7047679

CCCCCCCCCCCCCCCC(=O)NC=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.59
FAAH O00519 6/20 0.57
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
MAPK1 P28482 1/20 0.53
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
TRPA1 O75762 1/20 0.48
PPARG P37231 6/20 0.48
PPARD Q03181 6/20 0.48
PPARA Q07869 6/20 0.48
HDAC11 Q96DB2 5/20 0.48
TSHR P16473 4/20 0.48
GPR84 Q9NQS5 4/20 0.48
ALDH1A1 P00352 2/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
PTPN1 P18031 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10874849 1.00 HSP90AA1 (0.59) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL31260583 1.00 HSP90AA1 (0.59) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL27825865 1.00 HSP90AA1 (0.59) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL19545906 1.00 HSP90AA1 (0.59) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL16313624 1.00 HSP90AA1 (0.59) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL9407442 1.00 HSP90AA1 (0.59) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL11746035 1.00 HSP90AA1 (0.59) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL7518948 1.00 HSP90AA1 (0.59) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL28347031 0.98 HSP90AA1 (0.57) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL9365068 0.98 HSP90AA1 (0.56) HSP90AA1FAAHMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064954-A1 Cationic amphiphilic 1,4-dihydropyridine derivatives useful for delivery of nucleotide containing compounds SPONDULI SERVICES, LTD. (AU) 2003-04-03 US claimed
US-20030064954-A1 Cationic amphiphilic 1,4-dihydropyridine derivatives useful for delivery of nucleotide containing compounds SPONDULI SERVICES, LTD. (AU) 2003-04-03 US disclosed
EP-1261731-A1 CATIONIC AMPHIPHILIC 1,4-DIHYDROPYRIDINE DERIVATIVES USEFUL FOR DELIVERY OF NUCLEOTIDE CONTAINING COMPOUNDS Urtti, Arto (FI) 2002-12-04 EP disclosed
WO-2001062946-A1 CATIONIC AMPHIPHILIC 1,4-DIHYDROPYRIDINE DERIVATIVES USEFUL FOR DELIVERY OF NUCLEOTIDE CONTAINING COMPOUNDS URTTI ARTO (FI) 2001-08-30 WO disclosed
US-5576393-A NARROW PARTICLE SIZE DISTRIBUTION; EMULSION POLYMERIZATION RICOH COMPANY, LTD. (JP) 1996-11-19 US disclosed
US-5368972-A Method of preparing composite particles comprising adhering wax particles to the surface of resin particles RICOH COMPANY, LTD. (JP) 1994-11-29 US disclosed
US-4943506-A ELECTROGRAPHY, BINDER, SILICONE OIL PRETREATMENT MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1990-07-24 US disclosed
EP-0106465-B1 METHOD FOR DEVELOPING ELECTROSTATIC LATENT IMAGES MITA INDUSTRIAL CO. LTD. (JP) 1989-04-26 EP disclosed
EP-0103967-B1 PRESSURE-FIXING TONER FOR ELECTROPHOTOGRAPHY AND PROCESS FOR PREPARATION THEREOF MITA INDUSTRIAL CO. LTD. (JP) 1987-05-13 EP disclosed
EP-0059109-B1 DRY DEVELOPER FOR ELECTROSTATIC IMAGE MITA INDUSTRIAL CO. LTD. (JP) 1985-08-21 EP disclosed
US-4517274-A XEROGRAPHY, MAGNETIC BRUSH MITA INDUSTRIAL CO., LTD. (JP) 1985-05-14 US disclosed
EP-0062445-B1 METHOD OF DEVELOPING ELECTROSTATIC IMAGES MITA INDUSTRIAL CO. LTD. (JP) 1984-07-18 EP disclosed
EP-0106465-A2 Method for developing electrostatic latent images MITA INDUSTRIAL CO. LTD. (JP) 1984-04-25 EP disclosed
EP-0103967-A1 Pressure-fixing toner for electrophotography and process for preparation thereof MITA INDUSTRIAL CO. LTD. (JP) 1984-03-28 EP disclosed
US-4436803-A Method of developing electrostatic image with magnetic brush ear promoter MITA INDUSTRIAL CO., LTD. (JP) 1984-03-13 US disclosed
US-4415645-A PARTICLES OF A WAXY FIXATIVE DISPERSED IN A MOMOGENOUS MIXTURE OF RESIN AND PIGMENT; ANTIFOGGING AGENTS; TRANSFERRING MITA INDUSTRIAL COMPANY LIMITED (JP) 1983-11-15 US disclosed
US-4409312-A Dry developer for electrostatic image with Al or Ti alkoxide MITA INDUSTRIAL CO. LTD. (JP) 1983-10-11 US disclosed
US-4357406-A EMULSIFICATION, FIXING MITA INDUSTRIAL COMPANY LIMITED (JP) 1982-11-02 US disclosed
EP-0062445-A1 Method of developing electrostatic images MITA INDUSTRIAL CO. LTD. (JP) 1982-10-13 EP disclosed
EP-0059109-A1 Dry developer for electrostatic image MITA INDUSTRIAL CO. LTD. (JP) 1982-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030064954-A1 Cationic amphiphilic 1,4-dihydropyridine derivatives useful for delivery of nucleotide containing compounds ACIN1, DNA2, KPNA1 HSP90AA1 2228/4885FAAH 3445/4885MEN1 2117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.