KPNA1

Importin subunit alpha-5 · P52294 · KPNA1 on Sugi Atlas →

0 patent compounds predicted against KPNA1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to KPNA1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Hydroxychloroquine and Ivermectin for the Treatment of COVID-19 Infection PHASE3COMPLETED
Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria PHASE2COMPLETED
Selinexor With ICE Chemotherapy in Secondary Central Nervous System Involving B-cell Non-Hodgkin Lymphoma PHASE1/PHASE2RECRUITING
Efficacy of Ivermectin in COVID-19 PHASE1/PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma(SELINA) nanRECRUITING
Mechanisms of Resistance to Amivantamab in Patients With NSCLC With EGFR Exon 20 Insertion nanRECRUITING
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk nanNOT_YET_RECRUITING
Biomarker for Niemann Pick Type C Disease (BioNPC) nanWITHDRAWN
A Study on the Prevalence of Mutation of Cerebrotendinous Xanthomatosis (CTX) nanUNKNOWN
Biomarker for Sanfilippo Type A-B-C-D Disease (BioSanfilippo) nanWITHDRAWN
Whole Genome Sequencing in the Neonatal Intensive Care Unit nanCOMPLETED
Steroid Treatment of Idiopathic Nephrotic Syndrome nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Induced Pluripotent Stem Cells for Niemann Pick Disease nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Chordoma Family Study nanCOMPLETED
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Genetics of Ehlers-Danlos Syndrome nanCOMPLETED
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s) nanCOMPLETED
Phenotype/Genotype Correlations in Neuromuscular Disorders nanCOMPLETED
Comparative 2-D Tumor Analysis in Familial Gliomas nanCOMPLETED
Genetics of Neonatal Encephalopathy and Related Disorders nanRECRUITING
CoMPaSS-NMD - Computational Models for New Patients Stratification Strategies of HNMD nanENROLLING_BY_INVITATION
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Precision Genomics Medicine Biobank nanRECRUITING
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a KPNA1 binder may also engage these)

ProteinNameSimilarity
Q5R909 1.000 Q5R909 →
A2VE08 1.000 A2VE08 →
P83953 1.000 P83953 →
Q60960 1.000 Q60960 →
Q5RBV0 1.000 Q5RBV0 →
O35345 1.000 O35345 →
Q503E9 1.000 Q503E9 →
Q0V7M0 1.000 Q0V7M0 →
O15131 1.000 O15131 →
Q5ZML1 0.999 Q5ZML1 →
KPNA6 Importin subunit alpha-7 0.997 landscape →
Q56R16 0.992 Q56R16 →
P70188 0.947 P70188 →
O70133 0.946 O70133 →
E1C6Q1 0.945 E1C6Q1 →
Q7ZWU5 0.944 Q7ZWU5 →
O55029 0.944 O55029 →
Q92845 0.944 Q92845 →
P52297 0.944 P52297 →
Q3SZA0 0.941 Q3SZA0 →
O35116 0.940 O35116 →
AP2A2 AP-2 complex subunit alpha-2 0.940 landscape →
Q94899 0.940 Q94899 →
O88544 0.940 O88544 →
CTNNB1 Catenin beta-1 0.940 landscape →
Q9BQ87 0.940 Q9BQ87 →
GPS1 COP9 signalosome complex subunit 1 0.940 landscape →
Q5R648 0.940 Q5R648 →
Q6NRT5 0.939 Q6NRT5 →
Q68FK8 0.939 Q68FK8 →