Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BCL9 | O00512 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052204 | 0.85 | DGKA (0.50) | ALDH1A1CES2CES1LMNATSHR | |
| SCHEMBL7549027 | 0.83 | DGKA (0.53) | ALDH1A1CES2CES1LMNATSHR | |
| SCHEMBL7054538 | 0.83 | DGKA (0.53) | ALDH1A1CES2CES1LMNATSHR | |
| SCHEMBL7048641 | 0.83 | DGKA (0.53) | ALDH1A1CES2CES1LMNATSHR | |
| SCHEMBL2014240 | 0.83 | DGKA (0.53) | ALDH1A1CES2CES1LMNATSHR | |
| SCHEMBL27887514 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL9820088 | 0.80 | GAA (0.42) | ALDH1A1TSHR | |
| SCHEMBL9744519 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL27878053 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL23826 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CES2CES1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576776-B1 | Method of manufacture of 1,3-oxathiolane nucleosides | TRIANGLE PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
| EP-0797443-B1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIO-AVAILABILITY OF INOSITOL PHOSPHATE | BIONERIS AB (SE) | 2003-04-23 | — | — | EP | disclosed |
| US-5760022-A | ESTER, ETHER | PERSTORP AB (SE) | 1998-06-02 | — | — | US | disclosed |
| EP-0797443-A1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIO-AVAILABILITY OF INOSITOL PHOSPHATE | PERSTORP AB (SE) | 1997-10-01 | — | — | EP | disclosed |
| WO-1995019775-A1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIO-AVAILABILITY OF INOSITOL PHOSPHATE | PERSTORP AB (SE) | 1995-07-27 | — | — | WO | disclosed |