SCHEMBL7047836

SCHEMBL7047836

CC(=O)c1cc(C)c(-c2cccc3nc4ccccc4c(C(=O)O)c23)c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 4/20 0.43
KMT2A Q03164 3/20 0.43
TSHR P16473 1/20 0.40
PABPC1 P11940 1/20 0.40
DHODH Q02127 4/20 0.39
MEN1 O00255 2/20 0.39
LMNA P02545 2/20 0.39
TP53 P04637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.36
MYC P01106 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3904685 0.82 PDE10A (0.46) PDE10AKMT2ATSHRDHODHMEN1
SCHEMBL3907398 0.80 PDE10A (0.44) PDE10AKMT2ATSHRDHODHMEN1
SCHEMBL3900538 0.78 MAPT (0.45) PDE10AKMT2ATSHRMEN1NPC1
SCHEMBL7590081 0.75 PDE10A (0.58) PDE10AKMT2ATSHRDHODHMEN1
SCHEMBL29112020 0.75 KMT2A (0.43) PDE10AKMT2ATSHRMEN1LMNA
SCHEMBL3898412 0.74 RAB9A (0.58) PDE10AKMT2ADHODHMEN1LMNA
Hydrochloric Acid SCHEMBL9842693 0.74 PDE10A (0.57) PDE10AKMT2ATSHRDHODHMEN1
SCHEMBL10476973 0.74 DHODH (0.54) PDE10AKMT2ATSHRDHODHMEN1
SCHEMBL3109815 0.72 KDM4E (0.44) PDE10AKMT2ATSHRMEN1TP53
SCHEMBL4413030 0.72 RAB9A (0.39) PDE10AKMT2ATSHRDHODHMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609885-B1 Acridinium compounds and conjugates thereof MOCHIDA PHARM CO LTD (JP) 2003-04-16 EP disclosed
US-5594112-A CHEMILUMINESCENCE LABEL MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1997-01-14 US disclosed
US-5438139-A Chemiluminescent; useful as immunolochemical, DNA probe and receptor bininding assays MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1995-08-01 US disclosed
EP-0609885-A1 Acridinium compounds and conjugates thereof MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1994-08-10 EP disclosed