Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29112027 | 0.83 | KMT2A (0.34) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL7118784 | 0.80 | KDM4E (0.40) | KMT2AMEN1KDM4ELMNAPLA2G1B | |
| SCHEMBL7781667 | 0.78 | TERT (0.38) | LMNATTR | |
| SCHEMBL3904685 | 0.77 | PDE10A (0.46) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL4415782 | 0.76 | PREP (0.33) | — | |
| SCHEMBL7533773 | 0.75 | LMNA (0.38) | KMT2AMEN1KDM4ELMNAPLA2G1B | |
| SCHEMBL3907398 | 0.75 | PDE10A (0.44) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL3143334 | 0.75 | KDM4E (0.44) | KMT2AMEN1KDM4ELMNAPDE10A | |
| SCHEMBL3900538 | 0.73 | MAPT (0.45) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL8441018 | 0.73 | POLR1A (0.34) | KMT2AMEN1KDM4ELMNAPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298708-B1 | METHOD FOR DETERMINING THYROXINE UPTAKE | Ciba Corning Diagnostics Corp. (US) | 1992-11-11 | — | — | EP | claimed |
| US-20090318627-A1 | SOLID PHASE SYNTHESIS OF ACRIDINIUM DERIVATIVES | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2009-12-24 | — | — | US | disclosed |
| EP-1994007-A2 | SOLID PHASE SYNTHESIS OF ACRIDINIUM DERIVATIVES | Siemens Healthcare Diagnostics Inc. (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007092847-A2 | SOLID PHASE SYNTHESIS OF ACRIDINIUM DERIVATIVES | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2007-08-16 | — | — | WO | disclosed |
| US-4927769-A | OXIDIZING AN ACRIDINIUM ESTER IN THE PRESENCE OF A CATIONIC SURFACTANT, NONIONIC SURFACTANT OR SULFATED PRIMARY ALCOHOL | CIBA CORNING DIAGNOSTICS CORP. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4824777-A | Method for determining thyroxine uptake | CIBA CORNING DIAGNOSTICS CORP. (US) | 1989-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318627-A1 | SOLID PHASE SYNTHESIS OF ACRIDINIUM DERIVATIVES | ACR, SSU72, SP1 | RAB9A 3834/4885NPC1 2421/4885KMT2A 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.