Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | DRD5 | P21918 | 1/20 | 0.60 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11217331 | 0.88 | SSTR3 (0.64) | NR2E1DRD2DRD1DRD5SSTR3 | |
| SCHEMBL11204594 | 0.88 | NR2E1 (0.57) | NR2E1DRD2DRD1DRD5SSTR3 | |
| SCHEMBL11200910 | 0.83 | HTR2A (0.53) | NR2E1DRD2DRD1DRD5HCAR2 | |
| SCHEMBL2221885 | 0.83 | HCAR2 (0.49) | NR2E1DRD2DRD1DRD5SSTR3 | |
| SCHEMBL11203137 | 0.83 | RB1 (0.51) | NR2E1DRD2DRD1DRD5RB1 | |
| SCHEMBL11199712 | 0.83 | HTR2A (0.52) | NR2E1DRD2DRD1DRD5HCAR2 | |
| SCHEMBL20601973 | 0.83 | MAPT (0.54) | NR2E1DRD2DRD1DRD5KCNH2 | |
| SCHEMBL11197559 | 0.80 | HTR1D (0.53) | NR2E1DRD2DRD1DRD5HTR2A | |
| SCHEMBL11197826 | 0.80 | HTR1D (0.66) | DRD2DRD1DRD5HTR2AHTR2C | |
| SCHEMBL11194808 | 0.78 | HTR1D (0.45) | NR2E1DRD2DRD1DRD5HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030205696-A1 | Carbazole-based materials for guest-host electroluminescent systems | CANON KABUSHIKI KAISHA (JP) | 2003-11-06 | — | — | US | disclosed |
| EP-0073849-A1 | Novel phenyl-1,2,3,4-tetrahydrocarbazoles, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1983-03-16 | — | — | EP | disclosed |